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Flashcards in Dementia Deck (15):
0

Patient would likely dementia – next diagnostic steps? Probable treatment?

Assessment depression and reversible causes of dementia. AChE inhibitor

1

Work up for dementia?

CBC, ESR, BMP, TSH,

Infections: VDRL, HIV, urinalysis, CXR

Nutrition: B12 and folate

Head MRI/CT

2

Definition of dementia?

Impairment of memory and at least one other cognitive function without alteration of consciousness

3

Multi-infarct dementia?

Dementia in the setting of cerebrovascular disease, occurring after multiple cerebral infarctions

4

Delirium?

Acute or subacute onset of confusion with a fluctuating level of consciousness

5

Cognitive decline occurs with prominent mood disturbance consider? Tx?

Depression or pseudodementia (Treat with empiric Trial of antidepressants)

6

If patient has a history of irregular stepwise declining functioning or known cardiovascular disease/atrial fibrillation consider?

Multi-infarct dementia or Binswanger disease

7

Binswanger disease

Patient with long-standing hypertension or cerebrovascular disease who develops insidious, diffuse subcortical white matter changes

8

Common causes of dementia?

1. Depression
2. Multi-infarct dementia
3. Alcoholism
4. Parkinsonism

9

Infectious causes of dementia?

HIV dementia or neurosyphilis

10

Hormonal causes of dementia?

Hypothyroidism

11

Reversible form of dementia presents with a classic triad? Tx?

Normal pressure hydrocephalus. Classic triad of dementia, gate disturbance, and urinary or bowel incontinence (wet, wobbly, and wacky)

Treat with ventriculoperitoneal shunt

12

Treatment options for Alzheimer's disease?

Cholinesterase inhibitors: donepezil, rivastigmine, galantamine

NMDA antagonists: memantine

13

Drug to reduce psychotic symptoms and aggression in patients with dementia?

Risperidone

14

Common findings in brain imaging patients with Alzheimer's disease?

Enlarged cerebral ventricles and brain atrophy

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