Dermatology 1 Flashcards Preview

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Flashcards in Dermatology 1 Deck (19)
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0
Q

Melanoma confirmed - treatment?

If widespread?

Tends to metastasize to?

A

Wide excision

Interferon

Brain

1
Q

Patient with skin lesion positive for ABC and diameter over 6 mm - suspected diagnosis? Best initial step?

A

Melanoma; full thickness biopsy that removes entire lesion (not shave biopsy)

2
Q

Patient with history of organ transplant presents with skin lesion – suspected diagnosis? Typical description of lesson?

A

Squamous cell carcinoma; ulcer that does not heal

3
Q

Patient presents with waxy lesion, shiny like a pearl – suspected diagnosis?

Confirm diagnosis with?

Treatment?

A

Basal cell carcinoma; shave biopsy

Mohs micrographic surgery (no need for wide excision)

4
Q

Most common form of skin cancer?

A

Basal cell carcinoma

5
Q

Why is Kaposi’s sarcoma purpleish? Found in what organ systems?

Found in what type of AIDS?

A

More vascular

Skin, G.I. tract and lung

Sexual contact (not IV drug use)

6
Q

Treatment of Kaposi sarcoma ?

A
#Antiretrovirals – will treat majority of Kaposi Sarcoma
#Intralesional injections of vincristine or interferon
#If above fails, chemotherapy with liposomal doxorubicin
7
Q

Sun-exposed patient presents with erythematous/brownish plaque – likely diagnosis? Risk of? Management?

A

Curettage, cryotherapy, laser, 5-FU

Actinic keratosis (premalignant)

Squamous cell carcinoma

8
Q

Imiquimod used for?

A

Molluscum contagiosum and condyloma acuminata

9
Q

Hyperpigmented “stuck on” lesions – diagnosis? Management?

A

Seborrheic keratosis

Not premalignant - remove with surgery, cryotherapy or laser for cosmetic reasons

10
Q

Patient with history of asthma and allergic rhinitis – likely skin lesion? Onset? Natural history?

A

Atopic dermatitis (eczema)

Before five

1) Overactivity of mast cells leads to pruritis
2) pruritis leads to lichenification
3) scratching leads to potential infection

11
Q

Effect of food allergies on atopic dermatitis?

Immunoglobulin levels in atopic dermatitis?

Medical therapy?

A

None

Elevated IGE

#Topical steroids for flares
#Tacrolimus and pimecrolimus 
#Antihistamines
#Antibiotics for impetigo
#phototherapy for recalcitrant disease
12
Q

Tacrolimus and pimecrolimus - mechanism?

Potential complication?

A

T cell inhibiting Agents

Lymphoma

13
Q

Antihistamines to use in atopic dermatitis?

A

If mild - Nonsedating (loratidine, fexofenadine, certirizine)

If severe - hydroxyzine, diphenhydramine, doxepin

14
Q

Antibiotics for mild impetigo? Severe?

If MRSA?

A
#Bacitracin
#mupirocin (RNA-synthase inhibitor)
#retapamulin 
#Dicloxacillin 
#Cephalexin
#Docycycline
#clindamycin
#Bactrim
15
Q

Depression associated with this skin disease?

A

Psoriasis

16
Q

Psoriasis – treatment for local disease

Extensive disease?

A
#High potency steroid 
#Vitamin A and D (to help mitigate steroids)
#Coal tar
#Tacrolimus, and pimecrolimus for face and penis (to avoid steroids)
#UV light
#TNF inhibitors
# Methotrexate (last resort for psoriasis)
17
Q

Maculopapular syphilis-like a rash that spares palms and soles?

A

Pityriasis rosea

Transient but if symptomatic treat with steroids or UV light

18
Q

Seborrheic Dermatitis? Increased with what diseases? Treatment?

A

Hypersensitivity reaction to dermal infection from noninvasive dermatophytes

Parkinson’s and aids

#Steroids (cortisone, alclometasone)
#Antifungal agents (ketoconazole)

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