Flashcards in Dermatology 1 Deck (19):
Patient with skin lesion positive for ABC and diameter over 6 mm - suspected diagnosis? Best initial step?
Melanoma; full thickness biopsy that removes entire lesion (not shave biopsy)
Melanoma confirmed - treatment?
Tends to metastasize to?
Patient with history of organ transplant presents with skin lesion – suspected diagnosis? Typical description of lesson?
Squamous cell carcinoma; ulcer that does not heal
Patient presents with waxy lesion, shiny like a pearl – suspected diagnosis?
Confirm diagnosis with?
Basal cell carcinoma; shave biopsy
Mohs micrographic surgery (no need for wide excision)
Most common form of skin cancer?
Basal cell carcinoma
Why is Kaposi's sarcoma purpleish? Found in what organ systems?
Found in what type of AIDS?
Skin, G.I. tract and lung
Sexual contact (not IV drug use)
Treatment of Kaposi sarcoma ?
#Antiretrovirals – will treat majority of Kaposi Sarcoma
#Intralesional injections of vincristine or interferon
#If above fails, chemotherapy with liposomal doxorubicin
Sun-exposed patient presents with erythematous/brownish plaque – likely diagnosis? Risk of? Management?
Actinic keratosis (premalignant)
Squamous cell carcinoma
#Curettage, cryotherapy, laser, 5-FU
Imiquimod used for?
Molluscum contagiosum and condyloma acuminata
Hyperpigmented "stuck on" lesions – diagnosis? Management?
Not premalignant - remove with surgery, cryotherapy or laser for cosmetic reasons
Patient with history of asthma and allergic rhinitis – likely skin lesion? Onset? Natural history?
Atopic dermatitis (eczema)
1) Overactivity of mast cells leads to pruritis
2) pruritis leads to lichenification
3) scratching leads to potential infection
Effect of food allergies on atopic dermatitis?
Immunoglobulin levels in atopic dermatitis?
#Topical steroids for flares
#Tacrolimus and pimecrolimus
#Antibiotics for impetigo
#phototherapy for recalcitrant disease
Tacrolimus and pimecrolimus - mechanism?
T cell inhibiting Agents
Antihistamines to use in atopic dermatitis?
If mild - Nonsedating (loratidine, fexofenadine, certirizine)
If severe - hydroxyzine, diphenhydramine, doxepin
Antibiotics for mild impetigo? Severe?
#mupirocin (RNA-synthase inhibitor)
Depression associated with this skin disease?
Psoriasis – treatment for local disease
#High potency steroid
#Vitamin A and D (to help mitigate steroids)
#Tacrolimus, and pimecrolimus for face and penis (to avoid steroids)
# Methotrexate (last resort for psoriasis)
Maculopapular syphilis-like a rash that spares palms and soles?
Transient but if symptomatic treat with steroids or UV light