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Flashcards in Jaundice Deck (13):
0

Unconjugated hyperbilirubinemia? Causes?

Conjugated fraction <15% total

Hemolysis, Gilbert

1

Conjugated hyperbilirubinemia due to? Markers?

Hepatocellular disease (elevated AST and ALT) or biliary obstruction (alk phos)

2

Hemolysis/Gilbert: Bilirubin? Aminotransferases? Alk phos? Albumin? PT?

Indirect bilirubinemia, normal, normal, normal, normal

3

Acute hepatocellular necrosis: Bilirubin? Aminotransferases? Alk phos? Albumin? PT?

Bilirubinemia and bilirubinuria, ALT >AST >500, 5x normal)

4

Chronic hepatocellular disorders: Bilirubin? Aminotransferases? Alk phos? Albumin? PT?

Bilirubinemia and bilirubinuria, <3x normal values, decreased, prolonged and does not correct with vitamin K

5

Obstructive jaundice: Bilirubin? Aminotransferases? Alk phos? Albumin? PT?

Bilirubinemia and bilirubinuria, 4x normal elevation, normal, will correct with vitamin K

6

Infiltrative diseases or partial bile duct obstruction: Bilirubin? Aminotransferases? Alk phos? Albumin? PT?

Normal, normal, >4x normal, normal, normal

7

Patient with suspected biliary obstruction – test?

US

8

Extrahepatic dilatatiob without evidence of stones – test?

CT or ERCP

9

Strictures can result from?

1 PSC and PBC
2 surgery
3 pancreatitis
4 AIDS

10

PSC vs PBC: Age? Location? Associated conditions? Serologic markers? Complications?

Young males versus old females

Large intra/extra hepatic ducts versus small intrahepatic ducks

UC versus RA

None versus hentai mitochondrial antibody

Stricture/cholangitis/cholangiocarcinoma versus cirrhosis

11

Work up for patient with strictures but no history of surgery?

Look for cancer:
1 RUQ US to look at biliary tree
2 CT scan to visualize pancreas
3 FNA biopsy

12

Possible cure for pancreatic cancer?

Whipple procedure (pancreaticoduodenectomy)

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