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Flashcards in Jaundice Deck (13)
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0
Q

Conjugated hyperbilirubinemia due to? Markers?

A

Hepatocellular disease (elevated AST and ALT) or biliary obstruction (alk phos)

1
Q

Unconjugated hyperbilirubinemia? Causes?

A

Conjugated fraction <15% total

Hemolysis, Gilbert

2
Q

Hemolysis/Gilbert: Bilirubin? Aminotransferases? Alk phos? Albumin? PT?

A

Indirect bilirubinemia, normal, normal, normal, normal

3
Q

Acute hepatocellular necrosis: Bilirubin? Aminotransferases? Alk phos? Albumin? PT?

A

Bilirubinemia and bilirubinuria, ALT >AST >500, 5x normal)

4
Q

Chronic hepatocellular disorders: Bilirubin? Aminotransferases? Alk phos? Albumin? PT?

A

Bilirubinemia and bilirubinuria, <3x normal values, decreased, prolonged and does not correct with vitamin K

5
Q

Obstructive jaundice: Bilirubin? Aminotransferases? Alk phos? Albumin? PT?

A

Bilirubinemia and bilirubinuria, 4x normal elevation, normal, will correct with vitamin K

6
Q

Infiltrative diseases or partial bile duct obstruction: Bilirubin? Aminotransferases? Alk phos? Albumin? PT?

A

Normal, normal, >4x normal, normal, normal

7
Q

Patient with suspected biliary obstruction – test?

A

US

8
Q

Extrahepatic dilatatiob without evidence of stones – test?

A

CT or ERCP

9
Q

Strictures can result from?

A

1 PSC and PBC
2 surgery
3 pancreatitis
4 AIDS

10
Q

PSC vs PBC: Age? Location? Associated conditions? Serologic markers? Complications?

A

Young males versus old females

Large intra/extra hepatic ducts versus small intrahepatic ducks

UC versus RA

None versus hentai mitochondrial antibody

Stricture/cholangitis/cholangiocarcinoma versus cirrhosis

11
Q

Work up for patient with strictures but no history of surgery?

A

Look for cancer:
1 RUQ US to look at biliary tree
2 CT scan to visualize pancreas
3 FNA biopsy

12
Q

Possible cure for pancreatic cancer?

A

Whipple procedure (pancreaticoduodenectomy)

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