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Flashcards in Heme - Vasculitis Deck (20):
0

Nearly All vasculitis diseases present with?

#Fever
#Weight-loss
#Arthralgia/myalgia

1

Polyarteritis nodosa will never affect?

The lungs

2

Clinical features of polyarteritis nodosa?

#Renal – GN
#Neurologic – Mononeuritis multiplex (foot drop) or stroke in young person
#G.I. – abdominal pain worsened with eating; bleeding;
#Skin – lower extremity ulcers, livedo reticularis, purpura

3

Mononeuritis multiplex?

Multiple peripheral neuropathies of nerves large enough to have a name

4

Most accurate test to diagnose polyarteritis nodosa? Angiography would show?

Biopsy

Abnormal dilation (beading)

5

Best treatment for polyarteritis Nodosa?

Steroids and cyclophosphamide

6

Test all polyarteritis nodosa patients for?

Hepatitis B and C

7

Wegener's granulomatosis presents with what respiratory tract findings?

#Sinusitis
#otitis media
#Mastoiditis
#gingival involvement

8

ESR, CPK and aldolase in polymyalgia rheumatica? Treat with?

Elevated, Normal, normal

Steroids

9

Best initial test for Wegener's disease? Most accurate test for Wegener's disease?

C-ANCA

Lung biopsy > renal biopsy > sinus biopsy

10

Differentiating Churg Strauss from Wegener's?

Asthma and eosinophilia

11

Findings seen in HSP?

Skin purpura, joint arthralgia, hematuria, G.I. bleeding

12

HSP – do not test for? When to give steroids? Limitation of steroids?

IgA

Severe abdominal pain with progressive renal insufficiency

Will not reverse renal insufficiency



13

Cryoglobulinemia associated with?

#Chronic hepatitis C
#Endocarditis
#Connected tissue disorders – Sjögren's

14

Cryoglobulin versus cold agglutinin – associated with? Clinical manifestations? Treatment?

Hepatitis C versus EBV/mycoplasma/lymphoma

joint, kidney, skin, neuro findings versus hemolysis

Hep C meds versus rituximab, cyclophosphamide, cyclosporine

15

Behcet's syndrome?

Oral ulcers, arthritis, ocular lesions and pathergy

(Mouth, eyes, joints, skin)

16

Pathergy?

Sterile skin pustules from minor trauma with needlesticks

17

Ocular and cardiac findings of ankylosing spondylitis?

#Uveitis
#AV block or aortic insufficiency

18

Best initial test for ankylosing spondylitis? Most accurate test?

Best initial treatment?

X-ray of sacroiliac joint

MRI

Exercise and NSAIDs. If fails, anti-TNF

19

For seronegative arthropathies, do not treat with?

Steroids

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