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Flashcards in Heme - Vasculitis Deck (20)
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0
Q

Polyarteritis nodosa will never affect?

A

The lungs

1
Q

Nearly All vasculitis diseases present with?

A
#Fever
#Weight-loss
#Arthralgia/myalgia
2
Q

Clinical features of polyarteritis nodosa?

A
#Renal – GN
#Neurologic – Mononeuritis multiplex (foot drop) or stroke in young person
#G.I. – abdominal pain worsened with eating; bleeding;
#Skin – lower extremity ulcers, livedo reticularis, purpura
3
Q

Mononeuritis multiplex?

A

Multiple peripheral neuropathies of nerves large enough to have a name

4
Q

Most accurate test to diagnose polyarteritis nodosa? Angiography would show?

A

Biopsy

Abnormal dilation (beading)

5
Q

Best treatment for polyarteritis Nodosa?

A

Steroids and cyclophosphamide

6
Q

Test all polyarteritis nodosa patients for?

A

Hepatitis B and C

7
Q

Wegener’s granulomatosis presents with what respiratory tract findings?

A
#Sinusitis
#otitis media
#Mastoiditis
#gingival involvement
8
Q

ESR, CPK and aldolase in polymyalgia rheumatica? Treat with?

A

Elevated, Normal, normal

Steroids

9
Q

Best initial test for Wegener’s disease? Most accurate test for Wegener’s disease?

A

C-ANCA

Lung biopsy > renal biopsy > sinus biopsy

10
Q

Differentiating Churg Strauss from Wegener’s?

A

Asthma and eosinophilia

11
Q

Findings seen in HSP?

A

Skin purpura, joint arthralgia, hematuria, G.I. bleeding

12
Q

HSP – do not test for? When to give steroids? Limitation of steroids?

A

IgA

Severe abdominal pain with progressive renal insufficiency

Will not reverse renal insufficiency

13
Q

Cryoglobulinemia associated with?

A
#Chronic hepatitis C
#Endocarditis
#Connected tissue disorders – Sjögren's
14
Q

Cryoglobulin versus cold agglutinin – associated with? Clinical manifestations? Treatment?

A

Hepatitis C versus EBV/mycoplasma/lymphoma

joint, kidney, skin, neuro findings versus hemolysis

Hep C meds versus rituximab, cyclophosphamide, cyclosporine

15
Q

Behcet’s syndrome?

A

Oral ulcers, arthritis, ocular lesions and pathergy

Mouth, eyes, joints, skin

16
Q

Pathergy?

A

Sterile skin pustules from minor trauma with needlesticks

17
Q

Ocular and cardiac findings of ankylosing spondylitis?

A
#Uveitis
#AV block or aortic insufficiency
18
Q

Best initial test for ankylosing spondylitis? Most accurate test?

Best initial treatment?

A

X-ray of sacroiliac joint

MRI

Exercise and NSAIDs. If fails, anti-TNF

19
Q

For seronegative arthropathies, do not treat with?

A

Steroids

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