Flashcards in Heme - Vasculitis Deck (20):
Nearly All vasculitis diseases present with?
Polyarteritis nodosa will never affect?
Clinical features of polyarteritis nodosa?
#Renal – GN
#Neurologic – Mononeuritis multiplex (foot drop) or stroke in young person
#G.I. – abdominal pain worsened with eating; bleeding;
#Skin – lower extremity ulcers, livedo reticularis, purpura
Multiple peripheral neuropathies of nerves large enough to have a name
Most accurate test to diagnose polyarteritis nodosa? Angiography would show?
Abnormal dilation (beading)
Best treatment for polyarteritis Nodosa?
Steroids and cyclophosphamide
Test all polyarteritis nodosa patients for?
Hepatitis B and C
Wegener's granulomatosis presents with what respiratory tract findings?
ESR, CPK and aldolase in polymyalgia rheumatica? Treat with?
Elevated, Normal, normal
Best initial test for Wegener's disease? Most accurate test for Wegener's disease?
Lung biopsy > renal biopsy > sinus biopsy
Differentiating Churg Strauss from Wegener's?
Asthma and eosinophilia
Findings seen in HSP?
Skin purpura, joint arthralgia, hematuria, G.I. bleeding
HSP – do not test for? When to give steroids? Limitation of steroids?
Severe abdominal pain with progressive renal insufficiency
Will not reverse renal insufficiency
Cryoglobulinemia associated with?
#Chronic hepatitis C
#Connected tissue disorders – Sjögren's
Cryoglobulin versus cold agglutinin – associated with? Clinical manifestations? Treatment?
Hepatitis C versus EBV/mycoplasma/lymphoma
joint, kidney, skin, neuro findings versus hemolysis
Hep C meds versus rituximab, cyclophosphamide, cyclosporine
Oral ulcers, arthritis, ocular lesions and pathergy
(Mouth, eyes, joints, skin)
Sterile skin pustules from minor trauma with needlesticks
Ocular and cardiac findings of ankylosing spondylitis?
#AV block or aortic insufficiency
Best initial test for ankylosing spondylitis? Most accurate test?
Best initial treatment?
X-ray of sacroiliac joint
Exercise and NSAIDs. If fails, anti-TNF