Flashcards in MKSAP-Endo Deck (24):
LDL too high if?
LDL >130 in healthy pts
LDL >100 in high-risk patients
LDL >70 in extremely high-risk patients
Start fibrate therapy if?
Triglyceridemia>200 and Non-HDL cholesterol above goal (30 + LDL goal ~ 160 in healthy patients)
Or if patient has coronary heart disease equivalents (diabetes for referral vascular disease)
Five major cardiovascular risk factors?
Age (men >45 for women >55)
Non-HDL cholesterol goal in healthy patients? Formula?
30 + LDL goal
In patients with no risk factors, start statin if?
In diabetics, start statin if?
LDL>190 (optional below this)
Niacin in diabetics?
can cause glucose intolerance
Normal Values of TSH, T3, T4? (estimates)
Only test needed to diagnose hypothyroidism before treatment?
Radioactive iodine uptake scan; thyroglobulin (if suspect exogenous use)
Goal TSH, T4 ranges for pregnant patients? why?
TSH at low normal
T4 at 1.5 times normal (5-12 is normal)
Estrogen increases thyroid-binding globulin
Methimazole vs PTU
faster onset and fewer side effects vs PTU
Incidentally discovered adrenal adenoma - work up?
Most common abnormality associated with incidentalomas?
metanephrines and overnight Dexamethasone suppression test (rare for incidentalomas to make ALDO or androgens)
Metabolic syndrome criteria?
waist circumference >40
Greatest ways to reduce risk of developing diabetes in prediabetics?
Rosiglitazone/Pioglitazone (not used because high cost/side effects) > lifestyle changes > metformin
Metformin contraindicated with?
Cr>1.4 in women and 1.5 in men
Pt with diabetic retinopathy - mech? management?
neovascular proliferation; panretinal photocoagulation
Pt with advanced DM2 on insulin - do not?
switch to oral agents - glycemic control will deteriorate
Pt with HONK - how much fluid resuscitation? Do not give K until?
1/2 deficit in first 24 hours and rest over next 3 days
Urine output is verified
See xanthoma - expect elevation in (be specific)?
triglycerides > 3000
Thyroid nodule - when to biopsy? operate?
>1 cm; >4 cm
Lab values to diagnose primary hyperALDO?
ALDO/Renin > 20
Main causes of renovascular HTN in pt 55?
fibromuscular disease vs vascular disease
Suspected pheo - test?
CT>Metaiodobenzylguanidine (MIBG) scan
Pt with adrenal insufficiency in time of increased physiological stress (infection) - tx?
stress dose of steroids (10x normal dose in a day over 4 injections)