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Flashcards in Step Up: AKI Deck (10):
0

RIFLE criteria?

Risk 1.5 fold increase in creatinine for 6 hours
Injury: 2 fold increased creatinine for 12 hrs
Failure: 3 fold increase in creatinine for 24 hrs
Loss: Complete loss of function 4+ weeks
ESRD: Complete loss of function 3+ months

1

Most common clinical finding patients with AKI?

Weight gain and edema

2

Most common cause of death in a AKI?

Infection (75%)
Cardiorespiratory complications

3

Causes of hypovolemia?

Dehydration
Excessive diuretics
Vomiting
Diarrhea
Burns
Hemorrhage

4

Suspect patient is in prerenal failure – expect?

1. Oligoria
2. BUN:Cr >20:1
3. Increased urine osmolality >500
4. Decreased urine sodium <20

5

Causes of intrinsic renal failure?

1. ATN (ischemia, nephrotoxins)
2. Glomerular disease (Wegner's, poststreptococcal GN, Goodpasture's, lupus)
3. Vascular (renal artery occlusion, TTP, HUS)
4. Interstitial disease (hypersensitivity reaction)

6

Findings of rhabdomyolysis?

Acute kidney injury due to myoglobin toxicity

Increased CPK
Hyperkalemia
Hypocalcemia
Hyperuricemia

7

Treatment of rhabdomyolysis?

1. IV fluids
2. Mannitol
3. Bicarbonate (drives K back into cells)

8

Causes of nephrotoxic acute kidney injury?

1. Antibiotics (aminoglycosides, Vancomycin)
2. Radiocontrast
3. NSAIDs
4. Myoglobinuria
5. Hemoglobinuria
6. Cisplatin
7 Kappa abd Gamma light chains from multiple myeloma

9

Expected findings in interstitial acute kidney injury?

1. Oliguria
2. BUN:Cr40

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