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Flashcards in Onc - Solid Tumors Deck (23):
0

Breast cancer – best initial test? Most accurate test?

FNA biopsy; open biopsy

1

When to use an ultrasound for breast masses?

#Painful
#Varies in size or pain with menstruation

2

When to use a PET scan?

Determine content of the lymph nodes that are not easily accessible to biopsy

3

Importance of the negative sentinel node?

Eliminates the need for axillary lymph node dissection

4

ER or PR positive breast cancer patients should receive?

Tamoxifen, raloxifene, anastrozole, letrozole, exemestane)

5

Adverse effects of tamoxifen?

Adverse effects of aromatase inhibitors?

Endometrial cancer and clots

Osteoporosis

6

Went to adjuvant chemotherapy in breast cancer?

#Lesions larger than 1 cm
#Positive axillary lymph nodes

7

Patient with suspected prostate cancer – best initial test? Most accurate test?

Biopsy is best initial and most accurate

8

Erectile dysfunction is more common after surgery or radiation?

Surgery

9

Gleason grading is a measure of?

Hormonal medications for prostate cancer?

Malignant potential


#flutamide
#GnRH agonist
#Ketoconazole
#Orchiectomy

10

Management that is NOT beneficial in prostate cancer?

#Chemotherapy
#Hormonal drugs to prevent recurrences
#Screening imaging tests
#Lumpectomy

11

Age at which PSA is never done?

75+

12

Elevated PSA and palpable mass – next step?

Transrectal ultrasound –

#if mass, biopsy
#If no mass, multiple blind biopsies

13

In the lung cancer patients – surgery is not possible if,

#Bilateral disease
#Malignant effusion
#Heart, Carina, aorta or vena cava involved
#Small cell cancer

14

Typical presentation of ovarian cancer? Best initial test? Most accurate test?

Woman over 50 who presents with increasing abdominal girth but losing weight

Ultrasound or CT scan

Biopsy

15

Only cancer in which removing large amounts of locally metastatic disease has a benefit? Then treat with?

Ovarian cancer; chemotherapy

16

Patient presents with painless lump in the scrotum that does not transluminate – diagnostic testing?

Inguinal orchiectomy

17

Serum markers in testicular cancer?

#Alpha-fetoprotein in nonseminomatous tumors
#HCG in all

18

Testicular cancer metastasizes through? Into?

Lymphatic Channels in the retroperitoneum

The chest

19

Management of testicular cancer?

Orchiectomy followed by:
#Radiation if local disease
#Chemotherapy for widespread disease (one of the malignancies where metastasis can be cured with chemotherapy)

20

Management of cervical cancer?

Hysterectomy

21

Perform Pap smear when? Repeat how often? Until? Interval if you get Pap and HPV testing?

Age 21; every three years until age 65

Five-year interval with both

22

Pap smear shoes atypical squamous cell of undetermined significance - next step? Then?

HPV testing;

#if HPV is found, colposcopy
# if no HPV, repeat Pap smear at six months

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