Flashcards in Enzymes Deck (21):
enzymes that degrade phospholipids into fatty acids
catalyzes the formation or destruction of carbon-carbon bonds within a molecule.
Infection of the biliary tract results in release of beta-glucuronidase by injured hepatocytes and bacteria. Contributes to the hydrolysis of bilirubin glucuronides + increases the amount of unconjugated bilirubin in bile.
Function = oxidation of iodide to iodine + iodination of thyroglobulin tyrosine residues + iodotyrosine coupling reaction that forms T3 and T4.
Enzyme essential for function of lipase.
enzymes that hydrolyze phospholipids into fatty acids.
Catalyzes breakdown of complex carbohydrates.
cytochrome C oxidase
Last enzyme in respiratory electron transport chain of mitochondria. Receives an electron from each of four cytochrome C molecules and transfers them to one oxygen molecule, converting molecular oxygen to two molecules of water.
Initiates respiratory burst/intracellular killing. Generates superoxide anion by transferring electrons from NADPH, a reactive free radical.
Main role is to reduce hydrogen peroxide to water.
critical molecule in reducing oxidative stress
connection between HMP shunt and glutathione
HMP shunt generates NADPH which is used by glutathione reductase to regenerate glutathione, which is critical for resisting oxidative stress.
cofactor required by glutathione peroxidase and reducatse
where does respiratory burst happen?
hydrolyzes triglycerides in lipoproteins, such as those found in chylomicrons and VLDL into 3 fatty acids and one glycerol.
hormone-sensitive lipase. Intracellular lipase that hydrolyzes esters. *Hydrolyzes stored triglycerides in adipose tissue to free fatty acids.
Any enzyme that breaks a phosphodiester bond
Enzymes that cleave phosphodiester bonds within polynucleotide chain.