ID 11 Flashcards Preview

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Flashcards in ID 11 Deck (50):
1

HSV-1 route of transmission

respiratory secretions, saliva

2

HSV-1 causes...

1) gingivostomatitis
2) keratoconjunctivitis
3) herpes labials
4) herpetic whitlow
5) encephalitis

3

most common cause of sporadic encephalitis?

HSV-1

4

HSV-1 encephalitis presentation?

altered mental status + seizures + and/or aphasia

5

neonatal herpes caused by?

HSV-2

6

more common HSV causing viral meningitis?

HSV-2

7

VZV also known as

HHV-3

8

VZV can also cause

1) encephalitis
2) pneumonia

9

where does VZV establish latency?

dorsal root or trigeminal ganglia

10

EBV also known as..

HHV-4, herpes virus

11

EBV transmitted through

respiratory secretions, saliva

12

most common lymphadenopathy location for mono

posterior cervical nodes

13

CMV also known as...

HHV-5

14

CMV routes of transmission

1) congenital transfusion
2) sex
3) saliva
4) urine
5) transplant

15

CMV causes

1) mononucleosis with negative mono spot in immunocompetent patients
2) pneumonia in transplant patients
3) AIDS retinitis

16

where does CMV establish latency?

mononuclear cells

17

CMV retinitis presentation?

hemorrhage + cotton-wool exudates + vision loss

18

other name for roseola infantum

exanthema subitum

19

More common cause of roseola?

HHV-7

20

HHV-8 transmission?

sexual contact

21

where else can HHV-8 affect?

GI and lungs

22

what is capos sarcoma?

neoplasm of endothelial cells.

23

HSV diagnosis?

if on skin/genitalia --> viral culture
herpes encephalitis --> CSF PCR

24

Tzanck test used for..

HSV 1 and 2 and VZV

25

characteristic path finding with HSV

intranuclear inclusions

26

what receptor does CMV use?

integrins (heparan sulfate)

27

what receptor does rabies use?

nicotinic AChR

28

what receptor does rhinovirus use?

ICAM-1

29

What are the reoviruses?

1) coltivirus
2) rotavirus

30

Reovirus strcutre

NON enveloped
DS linear, 10-12 segments
Icosahedral capsid (double)

31

coltivirus causes..

colorado tick fever

32

#1 cause of fatal diarrhea in kids?

rotavirus

33

picornavirues

PERCH
Polio
Echovirus
Rhinovirus
Coxsackievirus
HAV

34

picornavirus structrue

NON enveloped
SS linear
Icosahedral capsid

35

Echovirus causes...

aseptic mengingitis

36

Coxsackievirus causes

1) aseptic meningitis
2) herpangina (mouth blisters, fever)
3) hand, foot, and mouth disease
4) myocarditis
5) pericarditis

37

HAV causes..

acute viral hepatitis

38

Hepevirus structure

non enveloped, SS, positive, icosahedral

39

caliciviruses

norovirus

40

flavivirus structure

*enveloped
SS, positive, linear, icosahedral capsid

41

faviviruses

HCV
Yellow fever
Dengue
*St. Lous encephalitis
West Nile virus

42

toga viruses...

Rubella
Eastern equine encephalitis
Western equine encephalitis

43

toga structure

*enveloped
SS, positive, linear, icosahedral capsid

44

retrovirus structure

*enveloped
SS, positive, linear, icosahedral capsid (HTLV), HIV = complex and conical capsid.

45

coronaviruses...

common cold
SARS
MERS

46

coronavirus structure

*enveloped
SS, positive, linear, *helical capsid

47

orthomyxovirus structure

*enveloped
SS, negative sense, linear, helical capsid, 8 segments

48

paramyxoviruses...

Parainfluenza (croup)
RSV
Measles
Mumps

49

Paramyxovirus structure

enveloped, SS, negative sense, linear, *helical capsid

50

aseptic meningitis

inflammation of the meninges with no bacterial source.