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Flashcards in ID 9 Deck (55):
1

giardia diagnosis

multinucleate trophozoites or cysts in stool

2

treatment for asymptomatic entamoeba cyst passers?

iodoquinol

3

entamoeba diagnosis

serology and/or trophozoites with engulfed RBCs in cytoplasm or cysts with up to 4 nuclei in stool

4

cryptosporidium treatment in immunocompetent host?

nitazoxanide

5

congenital toxo presentation

chorioretinitis + hydrocephalus + intracranial calcifications

6

toxo diagnosis

1) serology
2) *tachyzoites on biopsy

7

naegleria diagnosis

amoebas in spinal fluid

8

African sleeping sickness presentation

Enlarged lymph nodes + recurring fever (antigenic variation) + somnolence, coma

9

trypanosoma brucei diagnosis

trypomastigote in blood smear

10

trypanosoma treatment

blood borne disease --> suramin
melarsoprol --> CNS penetration

11

general malaria presentation

fever, headache, anemia, splenomegaly

12

p vivax/ovale cycle

48-hr cycle

13

p malaria cycle

72 hr (quartan)

14

P vivax/ovale findings

red granules (Schuffner stippling) throughout RBC cytoplasm

15

other malaria diagnosis

schizont containing merozoites

16

If resistant to chloroquine what do you use?

mefloquine or atovaquone/proguanil

17

If life-threatening malaria infection use...

IV quinidine or artesunate

18

other malaria drug you need to test for G6PD deficiency before using...

artesunate

19

what do you need to add for p vivax/ovale?

primaquine for hyponozite form

20

babesiosis presentation

fever + hemolytic anemia

21

RF for severe disease with babesiosis?

asplenia

22

babesiosis treatment

atovaquone + azithromycin

23

blood smear findings with babesiosis

ring form + maltese cross
*can also use PCR

24

trypanosoma cruzi diagnosis

trypomastigote in blood smear

25

drugs for trypanosoma cruzi

1) benznidazole
2) nifurtimox

26

visceral leishmaniasis presentation

spiking fevers + hepatosplenomegaly + pancytopenia

27

cutaneous leishmaniasis presents with...

skin ulcers

28

trichomonas causes...

vaginITIS. not vaginosis (gardnerella)

29

Describe immune response to helminths

Eosinophils act by type I and type II hypersensitivity reactions.
Type I --- neutralization of histamine and leukotrienes.
Type II -- eosinophils attach to surface of helminths via IgE and release cytotoxins (eg, major basic protein) contained in their granules.

30

other name for type 3 collagen

reticular fibers

31

type 3 collagen staining

silver

32

type 3 collagen function

forms a framework mesh for collagen and elastic fibers

33

other name for enterobius vermicularis

pinworm

34

other name for ascaris

giant roundworm

35

ascaris diagnosis

eggs visible in feces under microscope

36

other name for strongyloides

threadworm

37

strongyloides presentation

vomiting + diarrhea + epigastric pain (may mimic peptic ulcer)

38

strongyloides treatment

Ivermectin OR bendazoles

39

cutaneous larva migrant?

pruritic serpiginous (leaves scar tissue below while continuing to affect tissue above) rash caused by ancylostoma from walking barefoot on contaminated beach.

40

anyclostoma/necator treatment

bendazoles or pyrantel pamoate

41

trichinella treatment

bendazoles

42

trichinosis prsentation

fever + vomiting + nausea + *periorbital edema + myalgia

43

trichinella pathophys

infect intestine --> larvae enter bloodstream and encyst in striated muscle cells --> inflammation of muscle

44

disease caused by toxocara canis?

visceral larva migrans

45

visceral larva migrant pathophys

nematodes migrate to blood through intestinal wall causing inflammation and damage. Affects heart (myocarditis), liver, CNS (seizures, coma)

46

onchocerca treatment

ivermectin

47

onchocerca presentation

skin changes, loss of elastic fibers, river blindness.

48

potential sequela of onchocerca..

allergic reaction to microfilaria

49

onchocerca vector

female blackfly

50

loa loa presentation

when in skin --> swelling
or worm in conjunctiva

51

loa loa vector

deer fly
horse fly
mango fly

52

loa loa treatment

diethylcarbamazine

53

elephantiasis timeframe

takes about a year to become symptomatic

54

wuchereria bancrofti treatment

diethylcarbamazine

55

wuchereria bancrofti vector

female mosquito