Lesson 1B (Part 3) Flashcards Preview

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Flashcards in Lesson 1B (Part 3) Deck (12)
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1

Hepatic failure

Is the inability of the liver to perform its normal synthetic and metabolic function as part of normal physiology

2

What are the 2 forms of recognized hepatic failure?

1. Acute
2. Chronic

3

Acute liver failure

The rapid development of hepatocellular dysfunction, specifically coagulopathy and mental status changes in a patient without known prior liver disease

4

What are the potential causes of chronic liver failure? (8)

1. Excessive alcohol intake
2. Hepatitis B or C
3, Autoimmune, hereditary and metabolic causes
- eg. iron or copper overload
4. Steatohepatitis or non-alcoholic fatty liver disease
5. Worsening jaundice
6. Coagulopathy
7. Hepatic encephalopathy
8. Drug toxicity

5

When do ascites typically occur?

Secondary to liver cell failure

6

What is coagulopathy also known as?

Clotting and bleeding disorder

7

Coagulopathy

The bloods ability to clot is impaired

8

Hepatic encephalopathy

Is a decline in brain function that occurs as a result of severe liver failure
- patient exhibits confusion, altered levels of consciousness and coma

9

What is hepatic encephalopathy also called?

Hepatic coma

10

What percentage are drugs accountable for hepatic failure?

20-40%

11

Why are alcoholic persons susceptible to drug toxicity?

Because alcohol induces liver injury and cirrhotic changes that alters drug metabolism

12

What are the 2 outcomes for liver failure?

1. Liver transplantation
2. Death