Lesson 4C (Part 2) Flashcards

1
Q

Transitional Cell Carcinoma

A

Cancer that forms in the transitional cells in the lining of the bladder, ureter or renal pelvis

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2
Q

TCC

A

Transitional Cell Carcinoma

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3
Q

What is the nature of TCC? (2)

A
  1. Multifocal

2. Bilateral

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4
Q

Who is TCC more common in?

A

Men

- 65 years of age

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5
Q

What is a symptom of TCC? (2)

A
  1. Flank pain

2. Gross or microscopic hematuria

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6
Q

What can fat within the renal sinus appear as?

A

A mass and simulate TCC

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7
Q

What is necessary to confirm TCC? (2)

A
  1. IVU

2. CT

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8
Q

What does TCC look like on US? (3)

A
  1. Discrete
  2. Solid
  3. Central hypoechoic renal sinus mass
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9
Q

What are 3 differential diagnosis for TCC?

A
  1. Blood clots
  2. Sloughed papillae
  3. Fungus balls
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10
Q

What does TCC rarely invade?

A

The renal pelvis

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11
Q

How much does ureteral TCC account for in all the upper urinary tract cancers?

A

1-6%

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12
Q

Who is most affect by ureteral TCC?

A

Men

- 50-70 years of age

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13
Q

What are the S/S of ureteral TCC? (4)

A
  1. Hematuria
  2. Frequency
  3. Dysuria
  4. Pain
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14
Q

What is the sonographic appearance of ureteral TCC? (3)

A
  1. Hydronephrosis
  2. Hydroureter
  3. Occasionally solid ureteral mass is seen
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15
Q

What is necessary with ureteral TCC? (2)

A
  1. IVU

2. Retrograde pyelography

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16
Q

What is the most common malignant tumour?

A

Bladder TCC

17
Q

Who is most affect by bladder TCC?

A

Men

- 60-70 years of age

18
Q

What part of the bladder is affect by TCC? (3)

A
  1. Trigone
  2. Lateral walls
  3. Posterior walls
19
Q

What are the S/S of bladder TCC? (4)

A
  1. Hematuria
  2. Frequency
  3. Dysuria
  4. Suprapubic pain
20
Q

What is easy to detect with a full bladder?

A

Detection of polypoid tumours

21
Q

What can help to demonstrate the vascular stalk (pedicle)?

A

Colour doppler

22
Q

What is necessary for the diagnosis of bladder TCC? (2)

A
  1. Cystoscopy

2. Biopsy

23
Q

What does bladder TCC look like sonographically? (2)

A
  1. Nonmobile focal mass ***

2. May calcify

24
Q

How do you tell if a mass can move or not?

A

Turn the patient into decubitus position

- if the mass moves its probably a clot

25
What is the differential diagnosis of bladder TCC? (9)
1. Cystitis 2. Wall thickening 3. Postradiation change 4. Blood clot 5. Invasive prostatic carcinoma 6. Lymphoma 7. Metastasis 8. Endometriosis 9. Neurofibromatosis
26
How much more common is bladder TCC compared to renal elvis TCC?
50x
27
Why is bladder TCC more common compared to renal elvis TCC?
Due to its larger surface area
28
Why is renal TCC 2-3X's more common than ureteral TCC?
Because of its multifocal and bilateral nature | - may develop upper tract lesion when bladder TCC is apparent
29
Bladder outlet obstruction
Blockage at the base of the bladder that reduces or prevents the flow of urine into the urethra
30
What are the causes of bladder outlet obstruction? (4)
1. Enlarged prostate 2. Stones 3. Tumours 4. Scar tissue