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Flashcards in Renal Deck (16):
1

How do you calculate renal blood flow

Rbf= (renal plasma flow) / (1-hematocrite)

2

Where do thiazides act

early distal convoluted tubular

3

Name an osomtoic diruetic and where does it act

Manital
Proximal tube and descending loop

4

What does Lithium do to kidneys

Antags vasopressin on principal cells of the collecting duct

Leads to a nephrogenic DI

5

This presents with gross hematuria, acute flank pain, and passing of tissue in urine

Papillary necrosis

Seen in Sickle cell, DM, Analgegic, and Acute obstructive pylo

SAAD PAPa (with papillary necrosisi)

6

What is the triad of fanconi syndrome

Polyuria
Acidosiis
Hypophosphotemia

7

What is a "fanconi like" syndrome

Lead poisoning effect on the kidney

8

What is renal papillary necrosis

sloughing of necrotic renal papilla

Can be triggered byinfections

s/s: hematuria, protinuria

9

What are s/s of hypokalemia and how can a thiazide cause it

Muscle weakness, cramps, possible rhabdo

Thiazides--> Inhibit Na/Cl--> ↑ RAS--> aldosterone dumps H and K

10

What does ADH ↑ reabsorbtion of

Water
Urea
*reuptake of urea increases the concentration gradient to maximally concentrate urine

11

How do ACE inhibitors change GFR

They prevent efferent arteriole vasoconstriction (normally mediated by angiotensin)

VERY CONTRA-INDICATED in renal artery stenosis

12

How do you calculate filtration fraction

FF= GFR/RPF

13

What type of kidney disea is goodpasture

Type 2 Hypersense (Ab vs BM)
--> Rapidly progressive (crescentic) Glomerulonephritis

Nephritic

14

What kind of lung problem is in goodpasture

Restrictive

15

How is immunofluorescence on goodpasture kidney

Linear IgG on kidney/alveolar basement membrane

16

If there is a congenital renal abnormality, what other anomaly is likely present

Uterine problems

Mesonephric and Paramesonephric development are closely linked