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Flashcards in Onc/Heme Deck (23):
1

This drug inhibits microtubules and the side effect is neurotoxicity

Vincristine

2

This is seen in down syndrome
Has a rapid onset of symptoms
multiple cell lines are decreased

ALL (12:21) or (9:22)
B-ALL more common

3

ALL stain

TDT

4

Where does ALL like to met

CNS
teste

5

Lead poisoining inhibits:

Delta- aminolevulinic acid dehydratase and ferrochelatase

*an early enzyme in the heme pathway

6

Findings in lead poisoing

Microcytic anemia with basophilic stippling

s/s peripheral neuropathy
metaphyseal deposits of lead

7

Lab findings in a lead poisoning

↑ ferritin (iron strorage)

↓ TIBC (less iron is in circulation)

8

This vasculitis is associated with eosinophilia and p-anca

churg strause

9

What gene has RB on it

13

10

What is associated with 50% of hodgkin disease

EBV

11

_______ is the most common lung cancer type

Adenocarcinoma

12

Adenocarcinoma of the lung epidemiology

Happens in periphery of the lung
Usually women and NON smokers

13

This is a tumor often seen near the knee. More frequent in women 20-40
oval or spindle shaped cells

Giant cell tumor

"double bubble, or bubble sign"

14

What is characteristic of neurofibromatosis type 1

neurofibromas
cafe au late spots
Lish Nodules- spots on the eye

15

What causes the problem in NF-1

loss of NF-1 tumor suppressor on chromosome 17

16

What are all the things that can make G6PD hemolysis your blood

PAINS

Primaquine
Aspirin/nsaids
Ibuprofen
Nitrofurantoin (antibiotic)
Sulfonamide

17

What is the inheritance of vWF deficiency

Autosomal Dominant

18

What is missing in CGD

dysfx NADPH oxidase of monocyte

19

When would you see increased lymphs with smudge cells

CLL

the smudge cells have a weak membrane and fall apart easily

20

What has a 15:17 translocation

M3 type AML

21

Define PICA

compulsive consumption of non food OR non staple food (like eating ice cream only) for over 1 month

22

Who tends to get PICA

Pregos
School children
Results from iron deficiency anemia

23

What do people with pica like to eat

Soil
Starch (like cornstarch)
Ice