Test 61: all Flashcards

1
Q

3 year old, has: intellectual disability, gait or posture abnormality, eczema, and musty body odor

A

phenylketonuria

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2
Q

What is X-linked (Bruton) agammaglobulinemia ? mutation in what

A

defect in B cell maturation

- Burton tyrosine kinase gene

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3
Q

Staph. aureus in an IV drug user hurts what valve

A

tricuspid valve

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4
Q

Absolute risk reduction equation

A

event rate in the central group - event rate in treatment group

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5
Q

patient presenting with skeletal abnormalities, lens dislocation, intellectual deficits, vascular thrombosis and genetic defect in cystathionine beta-synthase enzyme

A

Homocystinuria

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6
Q

Pleiotrophy

A

multiple phenotypic manifestations result from single genetic mutation

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7
Q

When do children develop an understanding of concept of gender

A

age 3-4

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8
Q

first line therapy for Lyme disease? contraindications?

A

Doxycycline - contraindicated in pregnancy due to tooth discoloration
- give Amoxicillin

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9
Q

Burkitt lymphoma and nasopharyngeal carcinoma is related to what virus

A

EBV

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10
Q

Postauricular and occipital lymphadenopathy is common in what virus

A

rubella, togavirus

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11
Q

What does pyruvate kinase convert

A

Phosphoenolpyruvate to pyruvate

- generate ATP

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12
Q

Role of splenic red pulp

A

remove damaged RBC

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13
Q

what values are changed due to sickling episodes that result in hemolysis

A
  • increase indirect bilirubin and lactate dehydrogenase

- decrease levels of haptoglobin

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14
Q

Where are dietary lipids digested

A

duodenum

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15
Q

where are fatty acids passively absorbed

A

jejunum

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16
Q

SLE impact on complement

A

reduce rerum complement levels

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17
Q

Anti-cyclic citrullinated peptide antibodies are found in what

A

rheumatoid artheritis

18
Q

About half is sudden infant death syndrome is due to what

A

tobacco exposure

19
Q

What runs through the hepatoduodenal ligament

A

portal triad

20
Q

Pringle maneuver: occlusion of portal triad to distinguish the source of right upper quadrant bleeding. If bleeding persists, what is the source of blood

A
  1. inferior vena cava or hepatic veins
21
Q

LH stimulates what in the ovaries

A

-theca internal cells, produce androgens

22
Q

What does FSH do in ovaries

A

converts androgen to estrogen via aromatase

23
Q

What type of drug is Buspirone and MOA

A
  • nonbenzodiazepine anxiolytic

- stimulates 5-HT1a receptors

24
Q

How long does it take for Buspirone to work

A

slow onset

25
Location of Wernicke area and what supplies it
superior temporal gyrus of temporal lobe | - middle meningeal artery
26
viridans streptococci dextrans adhere to what molecule
fibrin-platelet aggregates
27
If the patient cannot make a decision and has not prepared an advance directive, who do you listen to
1. spouse 2. adult children 3. parents 4. adult siblings
28
Goodpasture has antibodies against what
collagen type IV in lung or kidney
29
drug that causes arteriolar dilation, improves renal perfusion, and increases natriuresis in the case of hypertension
Fenoldapam
30
MOA of Fenoldapam
dopamine-1 receptor agonist
31
most gastric ulcers occur where in stomach
lesser curvature of stomach
32
what artery runs along the lesser curvature of stomach
left and right gastric arteries
33
damage to what pleura can cause phrenic nerve irriation
diaphragmatic pleura and mediastinal pleura
34
familial dysbetalipoproteinemia have what serum levels
increase cholesterol and triglyceride levels
35
What is defected in dysbetalipoproteinemia
ApoE3 and ApoD4 levels
36
Communicating hydroceles and indirect hernias are caused by what
incomplete obliteration of processus vaginalis
37
What is the homophiles influenza's capsule made out of
polyribosylribitol phosphate
38
Side effects of Ethambutol
optic neuropathy: color blindess, central scotoma, and decreased visual acuity
39
which side is the inferior vena cava to the vertebra
right to the vertebral body
40
At what level do the renal veins join in the IVC
L1/L2
41
at what level do the common iliac veins merge with IVD
level of L4