World assessment: block 2 Flashcards Preview

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Flashcards in World assessment: block 2 Deck (28):
1

what vitamins are deficient in alcoholics

folate and cobalamin

2

Someone who has difficulty chewing. Diplopia when reading or watching tv for long periods

myasthenia gravis

3

myasthenia gravis is associated with

- thymoma
- thymic hyperplasia

4

DiGeroge syndrome is failure to form what pouches

3 and 4

5

glucose, sodium and potassium levels in diabetic ketoacidosis

glucose: increase
potassium: increased, but depleted intracellular
sodium: decrease

6

MOA for Phenoxybenzamine? use

alpha adrenergic blocker
- pheochromocytoma preoperatively to prevent catecholamine

7

what chemo drug has toxicity

Cisplatin

8

MOA for Misoprostol

PGE1 analog
- stimulates gastric epithelial cell mucus production

9

what molecule is increased with aspirin

5-lipoxygenase

10

How do nitrate impact heart and left ventricular end systolic volume

- reflex tachycardia
- decrease left ventricular end systolic volume

11

Low calcium levels. low serum phosphours and PTH levels. Short stature, short fingers and round face

Albright hereditary osteodystrophy
pseudohypoparathyroidism type 1A

12

what are PTH and phosphours levels in vitamin D deficiency

elevated PTH with low phosphorus

13

Allelic heterogeneity

different mutations at the same genetic locus causes similar phenotypes

14

MOA for montelukast

antagnoizes leukotriene D4 at cysteinyl-leukotriene receptor

15

triad for hemochromatosis

-cirrhosis
- diabetes mellitus
- skin pigmentation ( bronze diabetes)

16

Sites of anastomoses for portal system

- esophagus
- umbiliucs
- recuts
- spleen

17

what does ELISA detect

- specific antibody or antigen

18

Someone who has head circumference at 90th percentile, mid-face hypoplasia, and humoral/femoral shortening. Shortened digits and space between 3rd and 4th digits

achondroplasia

19

Tyrosine kinase activated in CD-19 positive cells by antigen exposure, resulting in cell maturation, if this defective what is most likely

X-linked Bruton agammaglobulinemia

20

proteins destined for rough ER posses

hydrophobic, N-terminal peptide signal sequnce
- remove this sequence get accumulation in cytosol

21

What vitamin is needed for branched-chain alpha ketoacid dehydrogenase

B1 thiamine

22

fetal ultrasound demonstrates
- ascites
- large bilateral pleural effusions
- small pericardial effusion

hydrops fatlis

23

glucagon uses what signaling pathway

- cAMP

24

hyperhidrosis

excessive sweating

25

ablation of what can be used to treat severe cases of axillary hyperhidrosis

thoracic sympathetic trunk
(postganglionic cholinergic neurons)

26

how does the round ligament course

- through inguinal canal into labia major

27

what is vanillymandelic acid

- degradation products of epinephrine and norepinephrine

28

Pulmonary embolism does what to acid base of body

- pulmonary embolism