Auto-antibodies Flashcards Preview

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Flashcards in Auto-antibodies Deck (22):
1

anti-ACh receptor

Myasthenia gravis

2

anti-basement membrane

Goodpasture

3

anti-cardiolipin, lupus anticoagulant

SLE, antiphopholipid syndrome

4

anti-centromere

Limited scleroderma (CREST syndrome)

5

anti-desmoglein

Pemphigus vulgaris

6

anti-dsDNA, anti-Smith

SLE

7

anti-glutamate decarboxylase

T1DM

8

anti-hemidesmosome

Bullous pemphigoid

9

anti-histone

Drug induced lupus

10

anti-Jo-1, anti-SRP, anti-Mi-2

Polymyositis, dermatomyositis

11

anti-microsomal, anti-thyroglobulin

Hashimoto's thyroiditis

12

anti-mitochondrial

Primary biliary cirrhosis

13

anti-nuclear antibodies

SLE, nonspecific

14

anti-Scl-70 (anti-DNA topoisomerase I)

Scleroderma (diffuse)

15

anti-smooth muscle

Autoimmune hepatitis

16

anti-SSA, anti-SSB (anti-Ro, anti-La)

Sjogren syndrome

17

anti-TSH receptor

Grave's disease

18

anti-U1 RNP

Mixed connective tissue disease

19

c-ANCA (PR3-ANCA)

Granulomatosis with polyangiitis (Wegener)

20

IgA anti-endomysial, IgA anti-tissue transglutaminase

Celiac disease

21

p-ANCA (MPO-ANCA)

Microscopic polyangiitis, Churg-Strauss syndrome

22

Rhematoid factor (IgM specific to IgG Fc region), anti-CCP

RA