Flashcards in 3/7 Deck (47)
What are the most common sx of a primary HSV infx?
Fever, vesiculoulcerative gingivostomatitis, cervical LAD
What are the most common sx of reactivation of a latent HSV infx?
More limited than a primary infx: periorbal blisters aka cold sores
What do multinucleated giat cells with intranuclear inclusions suggest?
HSV or VZV
Fever, vesiculoulcerative gingivostomatitis, and cervical LAD are suggestive of what infx?
Primary HSV infection (secondary would show perioral cold sores)
Where do HSV and VZV reside and reinfect from?
HSV: trigeminal ganglia
VZV: dorsal root ganglia
What sx are seen in reactivation of endogenous, latent CMV?
Interstitial pneumonitis, retinitis, hepatitis, colitis, and/or generalized disease
What lobe is affect in aspirations while standing? While supine?
Standing: basilar right lower lobe
Supine: posterior right upper lobe or superior right lower lobe
What receptors does NE have the most effect on?
Alpha1 and Beta1
What adrenergic receptor mediates vasoconstriction? Vasodilation?
Non selective, irreversible a1 and a2 receptor antagonist
Major use for Phenoxybenzamine?
Reversible, competitive a1, b1, b2 adrenergic receptor antagonist
For what sort of overdose would you give Labetalol?
Sympathomimetic overdose (e.g. cocaine)
Reversible, competitive, non specific alpha adrenergic antagonist
When might you give phentolamine?
Management of catecholamine-induced hypertensive crises (pheochromocytoma, MAOI crisis, cocaine overdose)
nonspecific beta adrenergic antagonist
Competitive muscarinic ACh R antagonist
What drug is a non selective, irreversible a1, a2 receptor antagonist?
What drug is a reversible, competitive a1, b1, b2 receptor antagonist?
What drug is a reversible, competitive, nonspecific alpha adrenergic antagonist?
What drug is a nonspecific beta adrenergic antagonist?
What drug is a competitive muscarinic ACh R antagonist?
What class is Quinidine?
What class is Lidocaine?
What class is Flecainide?
What class is verapamil?
What class is Esmolol?
Does amyloidosis cause restrictive or dilated cardiomyopathy?
What are some causes of restrictive cardiomyopathy?
Amyloidosis, sarcoidosis, cancer, inborn metabolic errors