Flashcards in Diuretics Deck (13):
A diuretic used for glaucoma, mountain sickness, and edema with alkalosis. Side effects include hyperchloremic metabolic acidosis and hepatic encephalopathy in cirrhotic patients.
MNEMONIC: ACIDazolamide causes ACIDOsis
True or False.
Efficacy of furosemide and hydrochlorothiazide is decreased by NSAIDs.
Loop diuretic toxicities: (6)
Allergy to sulfa
In the distal convoluted tubule, the calcium is also reabsorbed in this segment under the control of _____________ hormone.
Thiazide diuretics toxicity: (4)
Steroid inhibitor of cytoplasmic aldosterone receptors in cortical collecting ducts. Reduces potassium excretion.
Side effects include gynecomastia.
Spironolactone (aldosterone antagonist)
Inhibitor of ENaC in cortical collecting duct. Side effects include acute renal failure (with indomethacin).
Examples of potassium-sparing diuretics (4)
The K STAEs (stays) with K-sparing diuretics:
Which drugs (not necessarily diuretics) can cause gynecomastia?
DACKS (related to chicks):
Examples of osmotic diuretics (4)
Site of action of a ADH agonists and antagonists
Medullary collecting duct
Agonist at V1(blood vessel) and V2(collecting ducts) receptors. Activate insertion of aquaporin water channels in the collecting tubule.
Uses include central diabetes insipidus, nocturnal enuresis, hemophilia, and von Willebrand's disease.
Antidiuretic hormone a.k.a. vasopressin