Endo (Hypothalamic and Pituitary Hormones) Flashcards Preview

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Flashcards in Endo (Hypothalamic and Pituitary Hormones) Deck (13):
1

Increases release of IGF-1 in the liver and cartilage.
Used for GH deficiency, genetic diseases associated with short stature, failure to thrive, AIDS wasting

Somatostatin

2

Recombinant IGF-1 agonist

Mecasermin

3

GH receptor antagonist

Pegvisomant

4

Somatostatin analog
Suppresses secretion of GH, IGF-1, serotonin, and GI peptides

Octreotide

5

In men, _______ regulates spermatogenesis while _______ stimulates androgen production

FSH
LH

6

Used for infertility due to hypogonadism in men, used for ovulation induction in women
A. Follitropin Alfa
B. Choriogonadotropin Alfa
C. Leuprolide
D. Ganirelix
E. Bromocriptine
F. Oxytocin
G. Desmopressin
H. Conivaptan

Follitropin Alfa (FSH analog)

7

LH analog used for ovulation induction, hypogonadotropic hypogonadism
A. Follitropin Alfa
B. Choriogonadotropin Alfa
C. Leuprolide
D. Ganirelix
E. Bromocriptine
F. Oxytocin
G. Desmopressin
H. Conivaptan

Choriogonadotrophin Alfa

8

Used for precocious puberty, endometriosis, myocardial uteri, prostate cancer
SE: temporary exacerbation of precocious puberty or prostate cancer
A. Follitropin Alfa
B. Choriogonadotropin Alfa
C. Leuprolide
D. Ganirelix
E. Bromocriptine
F. Oxytocin
G. Desmopressin
H. Conivaptan

Leuprolide (GnRH analog)

9

Used for prostate cancer; prevents premature LH surge
Does not cause tumor flare-up when used for treatment of advanced prostate cancer
A. Follitropin Alfa
B. Choriogonadotropin Alfa
C. Leuprolide
D. Ganirelix
E. Bromocriptine
F. Oxytocin
G. Desmopressin
H. Conivaptan

Ganirelix (GnRH antagonist)

10

Used for hyperprolactinemia, prolactin-secreting pituitary adenoma, acromegaly, PD
A. Follitropin Alfa
B. Choriogonadotropin Alfa
C. Leuprolide
D. Ganirelix
E. Bromocriptine
F. Oxytocin
G. Desmopressin
H. Conivaptan

Bromocriptine (dopamine agonist)

11

An oxytocin-receptor blocker

Atosiban

12

Used for central diabetes insipidus, hemophilia A, von Willebrand's disease
A. Follitropin Alfa
B. Choriogonadotropin Alfa
C. Leuprolide
D. Ganirelix
E. Bromocriptine
F. Oxytocin
G. Desmopressin
H. Conivaptan

Desmopressin (ADH agonist)
(Increases factor VIII activity)

13

Used for SIADH, hyponatremia
A. Follitropin Alfa
B. Choriogonadotropin Alfa
C. Leuprolide
D. Ganirelix
E. Bromocriptine
F. Oxytocin
G. Desmopressin
H. Conivaptan

Conivaptan

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