First Aid Toxin Antidotes Flashcards Preview

USMLE Step 1 > First Aid Toxin Antidotes > Flashcards

Flashcards in First Aid Toxin Antidotes Deck (24)
1

Acetominophen (Tylenol)

N-acetylcysteine (replenishes glutathione)

2

Salicylates

NaHCO3 (bicarb) to alkalize urine, Dialysis

3

Amphetamines

NH4Cl (ammonium chloride) to acidify urine

4

AChE inhibitors, organophosphates

Atropine followed by pralidoxime

5

Antimuscarinic, anticholinergic agents

Physostigmine salicylate, control hyperthermia

6

Beta Blockers

Glucagon

7

Digitalis

LAMP: lidocaine, anti-dig Fab fragments, magnesium, normalize K+ (give potassium) and phenytoin if not responsive to lidocaine

8

Iron

Deferoxamine, Deferasirox

9

Lead

CaEDTA, dimercaprol, succimer, penicillamine

10

Mercury, arsenic, gold

Dimercaprol (BAL), succimer

11

Copper, arsenic, gold

Penicillamine

12

Cyanide

Nitrite + thiosulfate, hydroxocobalamin

13

Methemoglobin

Methylene blue, vitamin C

14

Carbon Monoxide

100% O2, hyperbaric O2

15

Methanol, ethylene glycol (antifreeze)

Fomepizole > ethanol, dialysis

16

Opioids

Naloxone/naltrexone

17

Benzodiazepines

Flumazenil

18

TCAs

NaHCO3 (bicarb) to alkalize plasma

19

Heparin

Protamine sulfate

20

Warfarin

Vitamin K, Fresh Frozen Plasma

21

tPA, streptokinase, urokinase

Aminocaproic acid

22

Theophylline

B-blocker

23

Hepatic encephalopathy

lactulose = disaccharide ==> acidification of gut lumen after breakdown by bacteria ==> trapping of ammonia

24

Serotonin syndrome

cyproheptadine = antihistamine w/anti-serotonin actions

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