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Flashcards in UWorld_3.25 Deck (11)
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1

Most common cause of elevated AFP on triple test

underestimation of fetal age ==> do US to confirm

2

Histo/gross path of late stage Type II DM

amyloid deposition @ pancreatic islet cells

3

Most important m. in performing valsalva maneuver

rectus muscle (abdominal)

4

Levels of reproductive hormones in menopause

-estrogen levels drop -FSH levels increase due to loss of feedback -LH levels increase later on, but less predictably

5

Muscles innervated by CN III

-inferior, superior, and medial rectus -inferior oblique -levator palpebrae -parasympathetic fibers ==> iris sphincter & ciliary muscle

6

Impact of cystic fibrosis mutation on channels

- ==> abnormalities in CFTR transmembrane protein - ==> decreased Cl- excretion ==> increased Na and water reabsorption (to balance) - ==> dehydrated/excess mucous

7

Cause of brown pigment stones

-secondary to infection of biliary tract -injured hepatocytes/bacteria ==> release of B-glucoronidase ==> increased unconjugated bilirubin @ bile

8

Selegiline: MOA

MAO-B inhibitor

9

Methotrexate toxicity antidote

Folinic acid

10

Cell types that cannot use ketone bodies as energy

-erythrocytes (no mitochondria) -hepatocytes (lacks thiophorase: succinyl-CoA - acetoacetate CoA transferase)

11

Neurologic problems in B12 deficiency

==> subacute degeneration ==> degeneration of both ascending (dorsal) and descending (corticospinal) pathways ==> loss of position/vibration sense, ataxia, and spastic paresis

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