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Flashcards in UWorld_2.13 Deck (7)
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1

Support/anchoring for actin filaments in muscle sarcomere

  • Z-line
    • lies in center of "lucent" I band

2

Characteristics of craniopharyngioma

  • calcified cystic tumors
  • arise from remnants of Rathke's pouch (<== embryonic precursor of anterior pituitary)
  • common present
    • H/A
    • growth failure
    • bitemporal hemianopsion=

3

Presentation of congenital hypothyroidism

  • hypotonia
  • "hoarse cry" @ birth
  • poor feeding
  • jaundice
  • macroglossia
  • constipation and umbilical hernia
  • increased incidence of heart defects: ASD, VSD

4

Common nerve block during childbirth + anotomic placement

  • pudendal nerve block <== often used if woman has progressed too far in labor to receive epidural anesthesia
    • pudendal = S2-S4
    • sensory info from perineum and genitals + motor innervation of spincter urethrae and external anal sphincter
  • administration
    • palapte ischial spines intravaginally
    • administer anesthetic @ that region

5

Nerves that innervate periuneum/genitals 

  • pudendal
  • genitofemoral
  • ilioinguinal

6

Endorphins/opiods molecular precursor and related molecules

  • proopiomelanocortin (POMC) ==>
    • beta-endorphins (opiods)
    • ACTH
    • MSH (melanocyte-stimulating hormone)

7

Toxins produced by Bordetella pertussis

  • pertussis toxin = disinhibits adenylate cyclase through Gi ADP-ribosylations
    • ==> increased cAMP levels ==> edema and phagocyte dysfxn
  • adenylate cyclase toxin = acts as adenylate cyclase
    • ==> increased cAMP levels ==> edema and phagocyte dysfxn

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