Rx_Random Set #3 Flashcards Preview

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Flashcards in Rx_Random Set #3 Deck (25)
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1

Adverse effects of phenytoin

  • gingival hyperplasia
  • megaloblastic anemia
  • teratogenesis
  • SLE-like sx

2

Infectious causes of dilated cardiomyopathy

coxsackievirus B 

3

Presentation of dilated cardiomyopathy

  • S3 heart sound
  • dyspnea
  • fluid overload + CHF
  • CHF ==>elevated b-type natriuretic peptide

4

elevated b-type natriuretic peptide indicates?

CHF

5

Most common cancer of bone

metastatic cancer >> primary cancer of bone

6

Older man + back pain + elevated alkaline phosphatase + bone lesions: Dx (most likely)?

metastatic neoplasia

7

Acute-phase cytokine

  • IL-6
    • produced by T lymphocytes

8

Common acute & chronic tx for Gout

  • NSAIDs
  • common acute: indomethacin
  • common chronic: probenecid

9

Common cause of this non-pruritic rash? + common patients w/condition?

  • Poxvirus (Molluscum contagiosum)
  • Patients:
    • children
    • immunosuppressed

10

Tumor @ cerebellopontine angle w/spindle cells + pink cytoplasm forming whorls and palisades on histology

Schwannoma

11

Common sx of schwannoma

  • dizziness
  • tinnitus
  • poor balance
  • hearing loss
  • increasing ICP

12

Characteristics of schwannoma

  • third most common primary intracranial tumor
  • often localized to cranial nerve VIII (acoustic neuroma)
  • commonly seen @ cerebellopontine angle

13

Muscular paraneoplastic syndrome derived from small cell lung cancer

  • Lambert-Eaton myasthenic syndrome
    • facial muscle or proximal muscle weakness
    • weakness improves with muscle use

14

Associations with Turner Syndrome

  • short stature
  • webbed neck
  • wide-set nipples
  • ovarian dysgenesis
  • bicuspid aortic valve
  • horseshoe kidney/renal abnormalities ==> WILMS TUMOR

15

Infectious cause (+ class of pathogen): Genital ulcer + pain + erythematous base + bleeds w/manipulation

  • Haemophilus ducreyi ==> Chancroid ulcers 
    • H. ducreyi = gram-negative coccobacillus

16

Characteristics of trichomoniasis

  • STD
  • sx:
    • vaginal itching
    • dysuria
    • foul-smelling green discharge
  • histopath:
    • trophozoites in vaginal discharge

17

Dx of Prerenal azotemia

  • urine osmolality > 500 mOSm/kg
  • urine Na+ < 20 mEq/L
  • fractional excretion of Na+ < 1%
  • serum BUN/Cr > 20

18

Characteristics of Whipple's disease

  • cause: T. whipplei
  • sx:
    • weight loss
    • diarrhea
    • arthralgias
  • histopath:
    • PAS-staining macrophages @ lamina propria on intestinal biopsy

19

Common complications of sickle cell trait

  • episodic hematuria
  • inability to concentrate urine
  • autosplenectomy at high altititudes

20

Tx of P. jiroveci infections in patients w/sulfa allergies

  • aerosolized pentamidine

21

Common diagnostic test for HIV

  • western blot
    • protein-antibody hybridization

22

Swimmer's ear: cause & tx

  • cause: Pseudomonas aeruginosa
  • tx: aminoglycoside + extended-spectrum penecillin
    • amino = gentamicin
    • ext-spec pen = piperacillin-tazobactam

23

Possible structural disruption w/surgical access to femoral artery

  • most likely = deep inguinal lymph nodes
    • inguinal lymph nodes enclosed inside the femroal sheath which must be opened to access femoral artery

24

Fetal vs. Adult Hemoglobin

  • Fetal = HbF-a2y2
    • increased affinity for oxygen vs. adult hemoglobin
    • ==> left shift in hte oxygen-hemoglobin dissociation curve
  • Adult = HbA

25

Causes of right shift of oxygen-hemoglobin dissociation curve

  • (Increase in) BAT ACE:
    • BPG (2,3 - BPG)
    • Altitude
    • Temperature
    • Acid
    • CO2
    • Exercise

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