Hallmarks Flashcards

Compiled hallmarks/gold standards/definitions

1
Q

presence of elongated, biconvex
transparent, needle shaped clefts which
represent chole crystals dissolved
during tissue processing

A

Atheroembolic disease

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2
Q

hallmark of APAS that is almost invariably

predictive of a poor outcome.

A

Livedo reticularis

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3
Q

Presence of patchy inflxy
infiltrates within interstititum (m.c. deep
cortex and outer medulla

A

AIN

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4
Q

infiltration of
inflammatory cells with associated edema,
which usually spares glomeruli and blood
vessels.

A

AIN

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5
Q

Loss of apical brush border of Prox Tub

cells is the Hallmark finding in

A

ATN

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6
Q

Unprovoked Hypokalemia

A

Hyperaldosteronism

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7
Q

hallmark renal
vascular lesionin px with uncomplicated
primary HPN

A

Afferent Arteriolar narrowing

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8
Q

an abnormal thirst
response in addition to variable defects in
AVP secretion

A

OSMORECEPTOR

DYSFUNCTION

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9
Q

urinary sodium (UNa) in reduced EABV

A

less than 15-20 mmol/L

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10
Q

inability to acidify the
urine appropriately during spontaneous or
chemically induced metabolic acidosis

A

classical hypokalemic distal

RTA

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11
Q

The pathologic sine qua non of minimal

change glomerulopathy

A

effacement of
visceral epithelial cell foot processes
observed by electron microscopy

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12
Q

ubiquitous clinical feature of the syndrome
is proteinuria which may be nephrotic or
nonnephrotic

A

FSGS

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13
Q

ubiquitous pathologic feature is focal
segmental glomerular consolidation or
scarring, which may have several distinctive
pattern

A

fsgs

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14
Q

mesangial interposition into an expanded
subendothelial zone that contains electrondense
immune complex deposit

A

Type 1 MPGN

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15
Q

The hallmark ultrastructural feature of PSGN

A

subepithelial humplike dense deposits

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16
Q

ubiquitous ultrastructural finding is
mesangial electron-dense deposits that
correspond to the immune deposits seen by
immunohistologic analysis

17
Q

Best diagnostic modality to dx papillary

necrosis in SC

18
Q

Gold standard for

identifying TRAS

A

DIGITAL intraarterial contrast

angiography

19
Q

golden standard- for
definition of vasc ana and stenotic
lesions in kidney

A

Intraarteral angio

20
Q

Vit D assay gold standard

21
Q

diagnostic procedure of

choice for nephrolith

22
Q

familial

hyperaldosteronism type I

A

Glucocorticoid-Remediable

Hyperaldosteronism

23
Q

Gordon’s Syndrome, Familial

Hyperkalemic Hypertension

A

Pseudohypoaldosteronism Type 2

24
Q

loss of function of EnAc

A

Pseudohypoaldosteronism Type 1

25
medial thickening and calcification of smaller elastic arteries
Mönckeberg’s calcification
26
white lines or keukonychia can develop during marked hypoalbuminemia
Muehrcke’s lines
27
chronic hypoalbuminemia may cause more difuse white nail
Terry’s or half and half nails
28
confer a peculiar susceptibility to the vascular effects of gram-negative endotoxin
Shwartzman phenomenon
29
autosomal dominant mutation of KCNJ2 encoding Kir 2.1 (periodic paralyisis, cardiac arrhythmia, dysmorphic features
Andersen’s syndrome
30
renal compression by a subcapsular mass or hematoma with hyperreninemia)
Page kidney