Hallmarks Flashcards

Compiled hallmarks/gold standards/definitions

1
Q

presence of elongated, biconvex
transparent, needle shaped clefts which
represent chole crystals dissolved
during tissue processing

A

Atheroembolic disease

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2
Q

hallmark of APAS that is almost invariably

predictive of a poor outcome.

A

Livedo reticularis

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3
Q

Presence of patchy inflxy
infiltrates within interstititum (m.c. deep
cortex and outer medulla

A

AIN

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4
Q

infiltration of
inflammatory cells with associated edema,
which usually spares glomeruli and blood
vessels.

A

AIN

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5
Q

Loss of apical brush border of Prox Tub

cells is the Hallmark finding in

A

ATN

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6
Q

Unprovoked Hypokalemia

A

Hyperaldosteronism

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7
Q

hallmark renal
vascular lesionin px with uncomplicated
primary HPN

A

Afferent Arteriolar narrowing

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8
Q

an abnormal thirst
response in addition to variable defects in
AVP secretion

A

OSMORECEPTOR

DYSFUNCTION

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9
Q

urinary sodium (UNa) in reduced EABV

A

less than 15-20 mmol/L

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10
Q

inability to acidify the
urine appropriately during spontaneous or
chemically induced metabolic acidosis

A

classical hypokalemic distal

RTA

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11
Q

The pathologic sine qua non of minimal

change glomerulopathy

A

effacement of
visceral epithelial cell foot processes
observed by electron microscopy

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12
Q

ubiquitous clinical feature of the syndrome
is proteinuria which may be nephrotic or
nonnephrotic

A

FSGS

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13
Q

ubiquitous pathologic feature is focal
segmental glomerular consolidation or
scarring, which may have several distinctive
pattern

A

fsgs

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14
Q

mesangial interposition into an expanded
subendothelial zone that contains electrondense
immune complex deposit

A

Type 1 MPGN

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15
Q

The hallmark ultrastructural feature of PSGN

A

subepithelial humplike dense deposits

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16
Q

ubiquitous ultrastructural finding is
mesangial electron-dense deposits that
correspond to the immune deposits seen by
immunohistologic analysis

A

IgA

17
Q

Best diagnostic modality to dx papillary

necrosis in SC

A

IVP

18
Q

Gold standard for

identifying TRAS

A

DIGITAL intraarterial contrast

angiography

19
Q

golden standard- for
definition of vasc ana and stenotic
lesions in kidney

A

Intraarteral angio

20
Q

Vit D assay gold standard

A

HPLC

21
Q

diagnostic procedure of

choice for nephrolith

A

CT scan

22
Q

familial

hyperaldosteronism type I

A

Glucocorticoid-Remediable

Hyperaldosteronism

23
Q

Gordon’s Syndrome, Familial

Hyperkalemic Hypertension

A

Pseudohypoaldosteronism Type 2

24
Q

loss of function of EnAc

A

Pseudohypoaldosteronism Type 1

25
Q

medial thickening and calcification of smaller elastic arteries

A

Mönckeberg’s calcification

26
Q

white lines or
keukonychia can develop during marked
hypoalbuminemia

A

Muehrcke’s lines

27
Q

chronic
hypoalbuminemia may cause more
difuse white nail

A

Terry’s or half and half nails

28
Q

confer a peculiar susceptibility to the
vascular effects of gram-negative
endotoxin

A

Shwartzman phenomenon

29
Q

autosomal
dominant mutation of KCNJ2 encoding
Kir 2.1 (periodic paralyisis, cardiac
arrhythmia, dysmorphic features

A

Andersen’s syndrome

30
Q

renal compression by a
subcapsular mass or hematoma with
hyperreninemia)

A

Page kidney