8.02 Antibacterials Flashcards Preview

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Flashcards in 8.02 Antibacterials Deck (15):
1

All cephalosporins are considered active against which species? (7)

LAME (A= atypical: chlamydia, mycoplasma)

1) Enterococci,
2) Listeria,
3) Legionella,
4) Chlamydia,
5) Mycoplasma,
6) MRSA
7) Acinetobacter

2

1st generation cephalosporins are resistant to what?

Staphylococcal Penicillinases

3

What is the DOC for surgical prophylaxis against gram +

Cephazolin

4

What is the clinical application of 2nd Generation Cephalosporins?

• Primarily used to treat sinusitis, otitis & lower
respiratory tract infections

5

prophylaxis & therapy of
abdominal and pelvic cavity infections

Cefotetan & cefoxitin

6

Ceftriaxone is the DOC for what?

N. Gonorrhea
N. Meningitis (ampicillin resistance H. Influ)

7

What other uses doe Ceftriaxone have beside Gono and Meningits?

Prophylaxis of meningitis in exposed individuals

Lyme Disease (CNS and joint infection)

8

Cefoperazone and Ceftazidime together are used to treat what?

P. Aeruginosa

9

How is Cefipime administered?

IV only

10

Which organisms does Cefepime target? (6)

1) Hemophilus
2) Niserria
3) E.Coli
4) Pneumococci
5) P.Mirabilis
6) P.Aeruginosa

11

What does Ceftraline have activity against?

MRSA

12

How are most Cephalosporins eliminated? Which are the exception and how are they eliminated?

-Kidney
-Ceftriaxone and Cefoperazone (Bile elimination)

13

Which cephalosporins are exceptions to parenteral administration?

-Cephalexin
-Cefaclor
-Cefixime

14

Which Cephalosporins contain methyl-thiotetrazole group? (3)

- Cefamandole
- Cefoperazone
- Cefotetan

15

What adverse effects are caused by Cephalosporins that contain methyl-thiotetrazole group? (2)

• hypoprothrombinemia (Vit. K1 admin can prevent)

• disulfiram-like reactions (avoid alcohol)