Flashcards in 9.1 Anti-Mycobacterials Deck (8):
Ethambutol inhibits which enzymes?
What is the most important Adverse Effect from Ethambutol?
• Dose-dependent visual disturbances (eg, red/green color blindness) – cannot be used in children too young to receive sight tests
Which anti-mycobacterial drug has adverse effects of nongouty polyarthralgia?
What is the MOA of Pyrazinamide?
Enzymatically hyrolyzed to active pyrazinoic acid
Which 3 drugs are recommended to be used in combination for Leprosy?
What is the mechanism of Dapsone?
• Inhibits folate synthesis (via dihydropteroate synthetase
What is acedapsone?
Repository form of dapsone