Pharm small group: Infectious Diseases 3 Flashcards Preview

Pharmacology > Pharm small group: Infectious Diseases 3 > Flashcards

Flashcards in Pharm small group: Infectious Diseases 3 Deck (20):
1

What is the recommended therapy for a pregnant woman with syphyllis?

single IM dose of Benzathine Penicillin G

2

What is the DOC for group A strep pharyngitis?

Penicillin V

3

What is another drug besides Penicillin V that can be used for treatment of GAS pharyngitis in young children?

Amoxicillin

4

For a patient who is unlikely to complete a full 10 day course of oral therapy for GAS pharyngitis, what is an alternative treatment?

Intramuscular benzathine penicillin G treatment

5

What may be used in patients with a type I hypersensitivity to penicillin's?

-Azithromycin
-Clarithromycin
-Clindamycin

6

What may be considered in a patient with a non-type I allergy to penicillin?

1st gen cephalosporin (cephalexin or cepadroxil)

7

What is the treatment for congenital syphillis?

-Aqueous penicillin G IV (10 days)
-Procaine penicillin G IM (10 days) - alternative

8

How does the PK of penicillin G benzathine differ from aqueous crystalline penicillin G?

When given IM, it is slowly released and hydrolyzed to Penicillin G. Result: lower plasma levels but much more prolonged.

9

What is the first line therapy for uncomplicated UTI?

Co-trimoxazole

10

What is used for complicated UTI?

Ciprofloxacin

11

Why should Ceftriaxone be withheld in a pregnant woman with a UTI who is close to parturition?

Possibility of neonatal kernicterus

12

Nitrofurantoin

- indication: UTI in pregnancy
- A.E: Hemolytic anemia in G6PD deficiency
- Contraindicated at term

13

Sulfanomide pregnancy UTI contraindications

- Near term
- breastfeeding
- < 2 months (except as adjunctive therapy with pyrimethamine to treat congenital toxo)

14

A.E. of sulfanomides when contraindicated for UTI's during pregnancy

Increase blood levels of unconjugated bilirubin and increase risk for kernicterus

15

DOC for Gonorrhea

Ceftriaxone plus doxycycline or azithromycin

16

DOC for chlamydia

Azithromycin or doxycycline

17

DOC for chlamydia in pregnancy

Azithromycin

18

DOC for Trichomoniasis

Metronidazole or tinidazole

19

DOC for Bacterial vaginosis

Metronidazole or clindamycin

20

DOC for chancroid

Azithromycin or Ceftriaxone or Ciprofloxacin or Erythromycin