Flashcards in Antiseizure Medications Deck (11):
The difference between simple partial and complex partial is that _________________.
simple partials entail preservation of consciousness
_____________ blocks the calcium-mediated release of glutamate.
Levetiracetam (though this mechanism is mostly unknown)
What drug is first-line treatment for tonic-clonic seizures?
Which antiepileptic is not metabolized by CYP?
What should be your approach to status epilepticus?
(1) Give a benzodiazepine.
(2) If that doesn't work, then add phenytoin.
(3) If that doesn't work, add phenobarbital.
(4) If that doesn't work, add pentobarbital or propofol.
The key feature for simple partial seizures is _________________.
preservation of consciousness
The main drug used for partial seizures is ___________. What are some alternatives?
carbamazepine; phenytoin, gabapentin, pregabalin, vigabatrin, tiagabine, levetiracetam, or lamotrigine
One of the big advantages of oxcarbazepine is _______________.
that it doesn't induce the CYP system
_________________ is the drug of choice for tonic-clonic seizures.
Why is clonazepam used in seizures more often than the other benzodiazepines?
Because clonazepam also blocks T-type calcium channels