Pharmacology of Reward Flashcards Preview

MS2 - Nervous System > Pharmacology of Reward > Flashcards

Flashcards in Pharmacology of Reward Deck (9):
1

The brain pathway central to the reinforcing effects of dopaminergic drugs is the _____________.

ventral tegmental area (VTA) to nucleus accumbens

2

The nucleus accumbens generates ____________.

drug-seeking behavior

3

In general, drugs with shorter half lives and faster onset of action have higher ________________.

abuse potentials

4

Dr. French notes that the amygdala is crucial in what aspect of reward association?

Integrative processing of associations; it does so by receiving input from the cortex and sending projections to the VTA

5

There are three areas of the prefrontal cortex that connect to the nucleus accumbens: the VMPFC, DLPFC, and OPFC. What is their collective function?

Regulating (OPFC), analyzing (DLPFC), and integrating (VMPFC) impulses with the emotional state – basically, learning to delay/deny gratification

6

The ____________ induces cravings and sends signals to the VTA and thence nucleus accumbens.

amygdala

7

All drugs that induce addiction do so by ________________.

increasing dopamine levels in the nucleus accumbens (some more directly than others)

8

Other than ketamine, there is another street drug that targets the NMDA receptor: ______________.

phencyclidine

9

When the amygdala secretes ____________ onto the VTA, then the VTA secretes dopamine onto the nucleus accumbens. Thus, this molecule is also implicated in pathologic learning.

glutamate

Decks in MS2 - Nervous System Class (111):