CNS Pharmacology Overview-Review Flashcards Preview

MS2 - Nervous System > CNS Pharmacology Overview-Review > Flashcards

Flashcards in CNS Pharmacology Overview-Review Deck (10):
1

Insomnia results from increased ______________.

acetylcholine (hence first-generation antihistamines – which are also anticholinergic – can treat insomnia)

2

Why would you give memantine to someone with Alzheimer's?

Because Alzheimer's presents with excess glutamate activity (and memantine is an NMDA receptor antagonist)

3

General anesthetics work by ________________.

blocking NMDA receptors, thus decreasing glutamate

4

What are the stages of anesthesia?

Stage I: analgesia and loss of consciousness
Stage II: unconscious but most reflexes preserved
Stage III: three planes, ranging from cessation of eye movements to paralysis of intercostal muscles
Stage IV: medullary paralysis

5

Increases in sodium chloride intake does what to lithium blood levels?

Decreases

6

True or false: weight gain is common in the first few months that a patient is taking an SSRI.

False. Generally, nausea and vomiting come in the first few months and weight gain happens after the first few months.

7

Review the "Lifetime U.S. Prevalence of Psychiatric Disorders" chart in Dr. Schneck's presentation.

Anxiety: 28.8%
Impulse control disorder (e.g., ADHD, ODD, CD): 24.8%
Any mood disorder: 21%
Major depressive disorder: 17%
Bipolar: 3.9%

8

Why does the VSCC-blocking action of lamotrigine aid in its treatment of epilepsy?

Because the VSCC cause glutamate release, and epilepsy is characterized by excess glutamate activity.

9

Recall that cocaine can also cause _______________ (not a sympathetic symptom).

seizures

10

Which antipsychotic is also a partial agonist at the D2 receptor?

Aripiprazole

Decks in MS2 - Nervous System Class (111):