Rotation: Pharmacology Flashcards Preview

MS2 - Nervous System > Rotation: Pharmacology > Flashcards

Flashcards in Rotation: Pharmacology Deck (22):
1

In addition to bethanecol, ___________ is also used to treat urinary retention.

neostigmine

2

____________ are used to shorten recovery time following surgeries needing to use paralytic drugs.

Neostigmine and edrophonium

3

___________ are the main treatment for myasthenia gravis, with cholinesterase inhibitors being merely an adjuvant therapy.

Immunotherapies

4

What is the most life-threatening effect of atropine overdose (and overdose of other muscarinic blocking agents)?

Hyperthermia

5

What do antimuscarinics do to the bowel and urinary system?

Cause constipation and urinary retention

6

If a patient can't tolerate the antimuscarinic side effects, then what novel therapy could be offered to treat overactive bladder?

Beta-3 agonists (mirabegron)

7

What are the symptoms of antimuscarinic activity in the CNS?

Sedation, delirium

8

Antimuscarinics are contraindicated in those with __________ (ophthalmologic issue) and ___________ (hyperplastic issue).

glaucoma; benign prostatic hyperplasia

9

Beta-2 activation leads to a __________ in total peripheral resistance.

decrease

10

Release of renin is mediated by which type of adrenergic receptor?

Beta-1

11

What receptor mediates increase of vitreous humor production?

Beta-2

12

Again, what does adrenergic stimulation do to the bladder?

Beta-2: relax the bladder muscle
Alpha-1: constrict the urethra

13

Which receptors can norepinephrine activate?

Beta-1 and alpha-1

14

Which receptors can epinephrine activate?

All adrenergic receptors

15

What receptor stimulation leads to relaxation of the uterine smooth muscle?

Beta-2

16

Which receptor stimulates ejaculation?

Alpha-1

17

What is the chemical category of physostigmine and neostigmine?

Carbamates

18

Oxymetazoline is what kind of drug?

Topical alpha-1 agonist

19

__________ can be used to treat "stage fright" and tremors.

Beta-blockers

20

Which kind of beta-blocker is used to treat cardiac conditions?

Beta-1 selective (so for angina and arrhythmias use beta-1s)

21

Which adrenergic drugs can be given to a patient with asthma?

Alpha-1 antagonists and beta-1 antagonists

22

Activation of alpha-2 receptors on cholinergic terminals in the GI tract leads to ____________.

decreased acetylcholine release

Decks in MS2 - Nervous System Class (111):