Flashcards in Rotation: Pharmacology Deck (22):
In addition to bethanecol, ___________ is also used to treat urinary retention.
____________ are used to shorten recovery time following surgeries needing to use paralytic drugs.
Neostigmine and edrophonium
___________ are the main treatment for myasthenia gravis, with cholinesterase inhibitors being merely an adjuvant therapy.
What is the most life-threatening effect of atropine overdose (and overdose of other muscarinic blocking agents)?
What do antimuscarinics do to the bowel and urinary system?
Cause constipation and urinary retention
If a patient can't tolerate the antimuscarinic side effects, then what novel therapy could be offered to treat overactive bladder?
Beta-3 agonists (mirabegron)
What are the symptoms of antimuscarinic activity in the CNS?
Antimuscarinics are contraindicated in those with __________ (ophthalmologic issue) and ___________ (hyperplastic issue).
glaucoma; benign prostatic hyperplasia
Beta-2 activation leads to a __________ in total peripheral resistance.
Release of renin is mediated by which type of adrenergic receptor?
What receptor mediates increase of vitreous humor production?
Again, what does adrenergic stimulation do to the bladder?
Beta-2: relax the bladder muscle
Alpha-1: constrict the urethra
Which receptors can norepinephrine activate?
Beta-1 and alpha-1
Which receptors can epinephrine activate?
All adrenergic receptors
What receptor stimulation leads to relaxation of the uterine smooth muscle?
Which receptor stimulates ejaculation?
What is the chemical category of physostigmine and neostigmine?
Oxymetazoline is what kind of drug?
Topical alpha-1 agonist
__________ can be used to treat "stage fright" and tremors.
Which kind of beta-blocker is used to treat cardiac conditions?
Beta-1 selective (so for angina and arrhythmias use beta-1s)
Which adrenergic drugs can be given to a patient with asthma?
Alpha-1 antagonists and beta-1 antagonists