Pharmacotherapy of Sleep Disorders Flashcards Preview

MS2 - Nervous System > Pharmacotherapy of Sleep Disorders > Flashcards

Flashcards in Pharmacotherapy of Sleep Disorders Deck (14):
1

What is the brand name of zolpidem?

Ambien

2

Eszopiclone is sold under the brand name ___________.

Lunesta

3

True or false: both benzodiazepines and zolpidem bind to the alpha-1 subunit.

True, but the Z drugs bind only to the alpha-1 subunit while benzodiazepines bind to alpha-1 to alpha-5.

4

Why would you be wary prescribing a daily dose of flurazepam?

Flurazepam has the longest half life; thus, regular doses can accumulate – particularly in the elderly.

5

Which drug is best for middle-of-the-night awakenings?

Zolpidem

6

Ramelteon is best for ______________.

problems with sleep onset

7

_____________ plays a key role in maintaining wakefulness throughout the day. Lack of it leads to narcolepsy.

Orexin

8

What is the mechanism of suvorexant?

It is an orexin receptor antagonist.

9

True or false: it is ok to chronically treat insomnia with antihistamines.

False.

10

One of the reasons the Z drugs are superior to benzodiazepines is that Z drugs have no effect on ____________, while benzodiazepines are known to decrease all three.

stages 3, 4, and REM sleep

11

The best Z drug for problems with sleep onset is _____________.

zaleplon ("to help with your zaleplONSET")

12

Why is triazolam prescribed more often than the other benzodiazepines in the treatment of insomnia?

Because it has a very short half-life (2.5 hours)

13

True or false: ramelteon is a controlled substance.

True

14

Doxylamine is an __________________.

antihistamine

Decks in MS2 - Nervous System Class (111):