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Flashcards in Blood Supply of the CNS Deck (5)

Why are arteries in the CNS more susceptible to HTN related injury?

They have quick transitions from large to small - low pressure to high pressure


What is unique about the BBB?

The capillary endothelial cells adhere to each other with tight junctions and astrocyte end feet surround the endothelium


How is the blood supply of the brain regulated?

- Metabolic
- Myogenic


What is the function of the BBB?

Restricts ionic/fluid movements, supplies essential nutrients,
mediates efflux of waste or toxic products


What is the composition of the BBB?

Capillary endothelial cells - pericytes, astrocytes and neuronal processes

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