Enteroviruses Flashcards Preview

Pathology > Enteroviruses > Flashcards

Flashcards in Enteroviruses Deck (20):
1

What disease does coxsackie virus cause?

Hand, foot and mouth disease

2

How is coxsackie virus spread?

Fecal-oral

3

What does D68 virus cause?

Respiratory Infection

4

What is pleconaril used to treat?

D68

5

Pleconaril MOA

It incorporates into virus particles, changes the shape of the particle, altered particle can not bind receptor and infect a new cell

6

What is transmitted via raw oysters?

Hepatitis A

7

What is the ROT of HepA?

Fecal-oral

8

What is the best for diagnosis of acute HepA infection?

IgM levels

9

What is unique about the HepA vaccine?

The vaccine is effective even after HepA exposure due to the latency of the virus

10

What is the HepA vaccine made from?

Killed virus

11

What does rotavirus cause?

Diarrhea often in young children

12

Where is the infection of rotavirus found?

Infection primarily restricted to villus epithelium of the small intestine

13

What is the pathogenesis of rotavirus diarrhea?

Rotavirus encodes a viral enterotoxin. The viral enterotoxin (NSP4) causes the diarrhea.

14

RotaTeq Vaccine

Live-attenuated, pentavalent vaccine for rotavirus

15

RotaRix Vaccine

Live-attenuated rotavirus vaccine based on the predominant G1 genogroup of rotaviruses

16

Reassortment occurs in which of these viruses:

A) Polioviruses and enteroviruses
B) Rotavirus and influenza virus
C) Yellow fever virus and Dengue virus
D) Ebola virus and Marburg virus
E) SARS coronavirus and MERS coronavirus

B) Rotavirus and influenza virus

17

• Resistant to environmental pressures:
drying, detergents, acids and temperature
• Transmitted by fecal-oral route
• Causes outbreaks of gastroenteritis
• Disease resolves after 48 hours - generally without serious consequences in healthy adults

Norovirus - cause of cruise ship diarrhea

18

Are there any treatments for rotavirus or norovirus?

No

19

Why is it important to determine if babies hospitalized for diarrhea are infected with rotavirus?

Children hospitalized with rotavirus infection should be isolated due to high incidence of nosocomial transmission.

20

Major characteristics of the enterovirus group of viruses include all of the following EXCEPT:

A. Fecal-oral route of transmission.
B. Acid stable virion.
C. Proteolytic processing of the viral polyprotein to yield capsid and nonstructural proteins.
D. Primary viremia leading to spread of the virus to target tissues.
E. Majority of infections result in frank cases of disease.

E. Majority of infections result in frank cases of disease.

Decks in Pathology Class (203):