Nakamura Human Anatomy Ch 24 Flashcards
(25 cards)
Kidneys
Maintain the chemical consistency of the blood
–Filter many liters of fluid from blood
–Send toxins, metabolic wastes, and excess water out of the body
–Main waste products
•Urea, uric acid, and creatinine
Organs of the urinary system
- kidneys
- ureters
- urinary bladder
- urethra (diff in male/female)
Location and external anatomy of kidneys
.Lateral to T12–L3 vertebrae (located at bottom of ribs)
•Average kidney – 12 cm tall, 6 cm wide, 3 cm thick
•Renal capsule surrounds the kidney
Not in the peritoneal cavity
Internal gross anatomy of the kidneys
Frontal section through the kidney –Renal cortex, renal pyramids, and renal pelvis •Nerve supply: renal plexus –A network of autonomic fibers –An offshoot of the celiac plexus
Nephron
- function unit
- approximately 1 million per kidney
- no veins, only arteries
- glomerular capsule: vessel/capillary network of arterioles (afferent and efferent)
Renal corpuscle
-glomerulus and glomerular capsule
–Glomerulus: tuft (a cluster) of capillaries
•Capillaries are fenestrated
-fed and drained by afferent and efferent arterioles
Glomerular (bowman’s) capsule
-Parietal layer: simple squamous epithelium
–Visceral layer: consists of podocytes (covering glomerular capillary)
Mechanisms of urine production
Filtration Reabsorption Secretion Body ph is 7.4 Protein has to have correct ph (it's structure depends on it)
Filtration
Filtrate of blood leaves kidney capillaries (GFR (glomerular filtration rate) = 180 L/day)
Reabsorption
Most nutrients, water, and essential ions reclaimed
- process of retiring filtered material to blood stream: 99% of what is filtered. Involve transport proteins
- 1% that is left forms urine (1.5 L)
Tubular section of nephron
.Filtrate proceeds to renal tubules from glomerulus –Proximal convoluted tubule –Loop of Henle •Descending limb •Thin segment •Thick segment –Distal convoluted tubule
Secretion
Active process of removing undesirable molecules
Classes of nephron
.Cortical nephrons – 85% of nephrons
•Juxtamedullary nephrons – 15% of nephrons
Collecting tubules (collecting ducts)
Receive urine from distal convoluted tubules
Microscopic blood vessels
- Nephrons associated with two types of capillary beds
- glomerulus
- peritubular capillaries - vasa recta
- juxtaglomerular apparatus (JGA)
- macula dense
Peritubular capillaries
In the cortex, arise from efferent arterioles
- low pressure, porous capillaries
- absorb salutes
Vasa recta
- in the medulla
- thin-walled looping vessels
- part of the kidney’s urine-concentrating mechanism
Juxtaglomerular apparatus (JGA)
- juxtaglomerular cells, macula dense, afferent and efferent vessels and mesangial cells
- functions in the regulation of blood pressure
Juxtaglomerular cells
Secrete renin
Macula dense
Portion of distal convoluted tubule
- tall, closely packed epithelial cells
- act as chemoreceptors (senses NaCl)
Ureters
Carry urine from the kidneys to the urinary bladder •Histology of ureter –Mucosa: transitional epithelium –Muscularis: two layers •Inner longitudinal layer •Outer circular layer
Urinary bladder
A collapsible muscular sac •Stores and expels urine –Full bladder: spherical •Expands into the abdominal cavity –Empty bladder: lies entirely within the pelvis
Urethra female
length of 3–4 cm
Urethra male
20 cm in length
three named regions
–Prostatic urethra: passes through the prostate gland
–Membranous urethra: through the urogenital diaphragm
–Spongy (penile) urethra: passes through the length of the penis