Brain Abscesses Flashcards Preview

Clinical Pathology > Brain Abscesses > Flashcards

Flashcards in Brain Abscesses Deck (15):
1

Commonest cause of brain abscesses

Streptococci

2

Causative organisms of brain abscesses

Streptococci
Staph A
gram -ve enteric bacteria (E.coli, pseudomonas)
Fungi
M. TB
Toxoplasma gondii

3

4 clinical explanations for brain abscesses

1. Direct spread from 'contiguous' supporative focus
2. Haematogenous spread from a distant focus e.g. endocarditis, bronchiectasis
3. Trauma
4. Cryptogenic- no explanation

4

Clinical presentation for brain abscesses

Headache, focal neurological deficit, confusion, fever, nausea, vomiting, dizziness, seizures, neck stiffness, papilloedema, coma

5

Management of small brain abscesses

Antibiotics

6

Management of large brain abscesses

Drainage, anitbiotics

7

Which drugs achieve therapeutic concentrations in intracranial pus?

Ampicillin, penicillin, cefuroxime, cefotazidime, metronidazole

8

Treatment for sinugenic/odontogenic abscess

Cefotaxime, metronidazole

9

Treatmnet for otogenic abscess

Benzylpenicillin, cetazidime, metronidazole

10

Complications of abscesses in the brain

Increased intracranial pressure
Ruptures (usually into ventricles) causing ventriculitis

11

Infection between dura and arachnoid mata

subdural empyema

12

Causes of subdural empyema

Strep.pneumo, H.influenzae, Staph A

13

Pathogeneisis of subdural empyema

Spread of infection from
sinuses
middle ear and mastoid
distant site e.g. haematogenous or following surgery or trauma

14

Cause of brain abscesses in neurosurgical patients

Ventriculoperitoneal shunt (VP) and external ventricular drain (EVD) infection

15

Most common causative organism of ventriculoperitoneal shunt and external ventricular drain?

Coagulase -ve staphylococci