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Flashcards in GI Pathology 2 Deck (48)
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1

Bling ended out pouchings of bowel

Diverticular disease

2

give an example of aquired diverticular disease

Meckle's

3

Where are diverticula commonly found?

Sigmoid colon, between mesenteric and anti-mesenteric taenia coli

4

What is the cause of diverticular disease

Uncoordinated peristalsis- increase in intraluminal pressure
Points of relative weakness in the bowel wall

5

Where in the bowel wall do penetrations occur?

At the arteries, where they enter the mucosa of the wall

6

Clinical presentation of diverticula disease

Cramping abdominal pain
Alternating diarrhoea and constipation

7

3 acute complications of diverticular disease

Diverticulitis/peridiverticular abscess
Perforation
Haemorrhage

8

4 chronic complicatioons of diverticular disease

Intestinal obstruction
Fistula
Diverticular colitis
Polypoind prolapsing mucosal fold

9

Which part of the bowel wall is colitis usually confined to?

Mucosa

10

Give 3 causes of acute colitis

Acute infection (camplylocbacter, salmonella, CMV)
Antibiotics
Drugs

11

Give a cause of chronic colitis

Chronic idiopathic inflammatory bowel disease

12

What 2 diseases come under idiopathic inflammatory bowel disease

Crohns and UC

13

Smoking is a) a risk factor, b)protective of which diseases

a) Crohns b)UC

14

Which part of the colon do you find UC

Starts in the rectum, spreads to a variable extent along colon

15

Crypt abscesses in crohn's or UC?

UC

16

Complications of UC

Toxic megacolon and perforation
Haemorrhage
Stricture
Carcinoma

17

What part of the GI tract does Crohn's affect?

Mouth to anus (most common form is ileocolic)

18

Skip lesions- discontinuous cobblestoning, and granulomas in UC or Crohn's

Crohn's

19

Mainly mucosal inflammation

UC

20

transmural inflammation

Crohn's

21

Anal lesions more common

Crohn's

22

Fistulae more common

Crohn's

23

Strictures more common

Crohn's

24

Serositis

Crohn's

25

Inflammatory polyps more common

UC

26

The name of the chronic liver disease, often in UC patients, which is a big risk factor for colorectal cancer

Primary sclerosing cholangitis

27

Types of colorectoal polyps

Pedunculated
Sessile
Flat

28

2 main types of non-neoplastic polyps

Hyperplastic
Hamartomatous

29

Describe hyperplastic polyps

1-5mm in size, often multiple. Only when large (>10mm) and on the right side are they capable of becoming malignant.

30

2 types of hamatomatous polyps

Peutz-jegher's
Juveline

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