Flashcards in GI Pathology 2 Deck (48)
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1
Bling ended out pouchings of bowel
Diverticular disease
2
give an example of aquired diverticular disease
Meckle's
3
Where are diverticula commonly found?
Sigmoid colon, between mesenteric and anti-mesenteric taenia coli
4
What is the cause of diverticular disease
Uncoordinated peristalsis- increase in intraluminal pressure
Points of relative weakness in the bowel wall
5
Where in the bowel wall do penetrations occur?
At the arteries, where they enter the mucosa of the wall
6
Clinical presentation of diverticula disease
Cramping abdominal pain
Alternating diarrhoea and constipation
7
3 acute complications of diverticular disease
Diverticulitis/peridiverticular abscess
Perforation
Haemorrhage
8
4 chronic complicatioons of diverticular disease
Intestinal obstruction
Fistula
Diverticular colitis
Polypoind prolapsing mucosal fold
9
Which part of the bowel wall is colitis usually confined to?
Mucosa
10
Give 3 causes of acute colitis
Acute infection (camplylocbacter, salmonella, CMV)
Antibiotics
Drugs
11
Give a cause of chronic colitis
Chronic idiopathic inflammatory bowel disease
12
What 2 diseases come under idiopathic inflammatory bowel disease
Crohns and UC
13
Smoking is a) a risk factor, b)protective of which diseases
a) Crohns b)UC
14
Which part of the colon do you find UC
Starts in the rectum, spreads to a variable extent along colon
15
Crypt abscesses in crohn's or UC?
UC
16
Complications of UC
Toxic megacolon and perforation
Haemorrhage
Stricture
Carcinoma
17
What part of the GI tract does Crohn's affect?
Mouth to anus (most common form is ileocolic)
18
Skip lesions- discontinuous cobblestoning, and granulomas in UC or Crohn's
Crohn's
19
Mainly mucosal inflammation
UC
20
transmural inflammation
Crohn's
21
Anal lesions more common
Crohn's
22
Fistulae more common
Crohn's
23
Strictures more common
Crohn's
24
Serositis
Crohn's
25
Inflammatory polyps more common
UC
26
The name of the chronic liver disease, often in UC patients, which is a big risk factor for colorectal cancer
Primary sclerosing cholangitis
27
Types of colorectoal polyps
Pedunculated
Sessile
Flat
28
2 main types of non-neoplastic polyps
Hyperplastic
Hamartomatous
29
Describe hyperplastic polyps
1-5mm in size, often multiple. Only when large (>10mm) and on the right side are they capable of becoming malignant.
30
