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Flashcards in Cytokines High Yield Deck (29):
1

What cytokine activates osteoclasts?

IL-1

2

What cytokine causes fever and acute inflammation?

IL-1
IL-6

3

What cytokine induces expression of acute phase reactants?

IL-6

4

What cytokine is a major chemotactic factor for neutrophils?

IL-8

5

What cytokine leads to differentation of T cells into Ih1 cells?

IL-12

6

What cytokine activates NK cells?

IL-12

7

What cytokine mediates septic shock?

TNF- alpha

8

What cytokine stimulates all types of T cells?

IL-2

9

What cytokine stimulates bone marrow stem cells (growth and proliferation)?

IL-3

10

WHat cytokine stimulates macrophages?

IFN- gamma

11

What cytokine stimulates IgE production?

IL-4

12

What cytokine induces differentiation into Th2 cells?

IL-4

13

What cytokine stimulates IgA production?

IL-5

14

What cytokine promotes differention of B cells?

IL-5

15

What cytokine promotes the GROWTH of B cells?

IL-4

16

Which cytokine decreases expression of MHC II and Th1 cytokines?

IL-10

17

Which cytokine inhibts activated macrophages and dendritis cells?

IL-10

18

What cells secrete IL-10?

Th2 cells and T regs

19

What cells secrete IL-1?

Macrophages

20

What cells secrete IL-2?

ALL T cells

21

What cells secrete IFN gamma?

Th1 cells

22

What cells secrete IL-6?

Macrophages

23

What cells secrete IL-3?

ALL T cells

24

What cells secrete IL-5?

Th2 cells

25

What cells secrete IL-8?

Macrophages

26

What cells secrete TNF- alpha?

Macrophages

27

What cells secrete IL-12?

Macrophages

28

Which cytokiness help protect against RNA and DNA viruses?

IFN alpha and IFN beta

29

What are interferon alpha and beta?

Glycoproteins--> act locally to prime cells for viral defense by degrading viral nucleic acid and protein

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