Flashcards in High Yield from Questions Deck (7)
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1
What mutation causes chronic granulomatous disease?
inactivating mutation affecting NADPH oxidase--> inhibits phagocytic intracellular killing
2
What types of organisms generate recurrent infections in people with chronic granulomatous disease?
catalase positive
3
Mucicarmine stain can help to identify which fungi?
Cryptococcus neoformans (polysaccharide capsule)
4
What bacteria cause intracellular infections? (8)
Chlamydia, legionella, Listeria, Mycobacterium, Neisseria meningitidis, Nocardia, Rickettsia, Salmonella typhi
5
What is the primary immune mechanism against intracellular infections?
Cell mediated immunity
6
Which Cephalosporins can treat pseudomonas?
Ceftazidime and defepine (3rd and 4th generation)
7
