High Yield from Questions

Question 1

What mutation causes chronic granulomatous disease?

Answer 1

inactivating mutation affecting NADPH oxidase–> inhibits phagocytic intracellular killing

Question 2

What types of organisms generate recurrent infections in people with chronic granulomatous disease?

Answer 2

catalase positive

Question 3

Mucicarmine stain can help to identify which fungi?

Answer 3

Cryptococcus neoformans (polysaccharide capsule)

Question 4

What bacteria cause intracellular infections? (8)

Answer 4

Chlamydia, legionella, Listeria, Mycobacterium, Neisseria meningitidis, Nocardia, Rickettsia, Salmonella typhi

Question 5

What is the primary immune mechanism against intracellular infections?

Answer 5

Cell mediated immunity

Question 6

Which Cephalosporins can treat pseudomonas?

Answer 6

Ceftazidime and defepine (3rd and 4th generation)

Question 7

Which cephalosporin is used to treat community aquired pneumonia?

Answer 7

Ceftriaxone