Flashcards in High Yield from Questions Deck (7)
What mutation causes chronic granulomatous disease?
inactivating mutation affecting NADPH oxidase--> inhibits phagocytic intracellular killing
What types of organisms generate recurrent infections in people with chronic granulomatous disease?
Mucicarmine stain can help to identify which fungi?
Cryptococcus neoformans (polysaccharide capsule)
What bacteria cause intracellular infections? (8)
Chlamydia, legionella, Listeria, Mycobacterium, Neisseria meningitidis, Nocardia, Rickettsia, Salmonella typhi
What is the primary immune mechanism against intracellular infections?
Cell mediated immunity
Which Cephalosporins can treat pseudomonas?
Ceftazidime and defepine (3rd and 4th generation)