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Flashcards in High Yield from Questions Deck (7)
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1

What mutation causes chronic granulomatous disease?

inactivating mutation affecting NADPH oxidase--> inhibits phagocytic intracellular killing

2

What types of organisms generate recurrent infections in people with chronic granulomatous disease?

catalase positive

3

Mucicarmine stain can help to identify which fungi?

Cryptococcus neoformans (polysaccharide capsule)

4

What bacteria cause intracellular infections? (8)

Chlamydia, legionella, Listeria, Mycobacterium, Neisseria meningitidis, Nocardia, Rickettsia, Salmonella typhi

5

What is the primary immune mechanism against intracellular infections?

Cell mediated immunity

6

Which Cephalosporins can treat pseudomonas?

Ceftazidime and defepine (3rd and 4th generation)

7

Which cephalosporin is used to treat community aquired pneumonia?

Ceftriaxone

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