G Protein Linked Secondary Messengers Flashcards
1
Q
Alpha 1
A
Gq
2
Q
alpha 2
A
Gi
3
Q
Beta 1
A
Gs
4
Q
Beta 2
A
Gs
5
Q
M1
A
Gq
6
Q
M2
A
Gi
7
Q
M3
A
Gq
8
Q
D1
A
Gs
9
Q
D2
A
Gi
10
Q
H1
A
Gq
11
Q
H2
A
Gs
12
Q
V1
A
Gq
13
Q
V2
A
Gs
14
Q
What is the mechanism of Gq?
A
Increase PHOSPHOLIPASE C–> increase DAG/ IP3–> Increased Ca
15
Q
What is the mechanism of Gs?
A
Increase adenylate cyclase–> increase cAMP
16
Q
What is the mechanism of Gi?
A
Decrease adenylate cyclase–> decrease cAMP
17
Q
What receptors are linked to Gq?
A
H1, alpha 1, V1, M1, M3
18
Q
What receptors are linked to Gs?
A
beta 1, beta 2, D1, H2, V2
19
Q
What receptors are linked to Gi?
A
M2, alpha 2, D2
