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Flashcards in Dermatology High Yield Deck (65)
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1

What are the layer os the epidermis from surface to base?

Stratum Corneum

Stratum Lucidum

Stratum Granulosum

Stratum Spinosum

Stratum Basale

2

"felt connecting ACTIN cytoskeletos of adjacent cells with Cadherins"

Tight junctions/ Zonula aderins

3

"structural support via KERATIN interactions"

Desmosome/ Macula adherens

4

"channel proteins called connexons permit electrical and chemical communication between cells"

gap junction

5

"connects keratin in basal cells to underlying basement membranes"

Hemidesmosomes

6

What cell junction is targeted in Bullous pemphigoides?

Hemidesmosomes

7

What cell junction is targeted in pemphigus vulgaris?

Desmosome

8

"prevents paracellular movement of solutes; composed of claudins and occludins"

tight junctions

9

"flat lesion with well circumscribed change in skin color"

macule

10

"macule

Patch

11

"elevated solid skin lesion

papule

12

"papule

plaque

13

"small fluid containing blister

vesicle

14

"large fluid containing blister >1cm"

bulla

15

"vesicles containing pus"

pustule

16

"transient smooth papule or plaque"

Hives

17

"flaking off of stratum corneum"

Scale--> eczema, psoriasis, SCC

18

"dry exudate"

crust

19

What is hyperkeratosis?

increased thickness of stratum corneum

20

What is parakeratosis?

hyperkeratosis with retention of nuclei in statum corneum

21

What is spongiosis?

epidermal accumulation of edematous fluid in intercellular spaces

22

What is acantholysis?

separation of epidermal cells

23

What is Acanthosis?

Epidermal hyperplasia

24

What is an example of acanthosis?

Acanthosis nigricans

25

"normal melanocyte number with decreased melanin production"

albinism

26

What is deficient or defective in albinism?

Tyrosinase enzyme

Tyrosine transport

27

"hyperpigmentation associated with pregnancy"

melasma

28

"irregular areas of complete depigmentation"

vitiligo

29

What causes vitiligo?

Autoimmune destruction of melanocytes

30

What type of hypersensitivity is atopic dermatitis (eczema)?

Type I

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