Teratogens High Yield Flashcards Preview

Step 1 Review > Teratogens High Yield > Flashcards

Flashcards in Teratogens High Yield Deck (23):
1

ACE inhibitors

renal Damage

2

Alkylating agents

absence of digits

3

Aminoglycosides

CN VIII toxicity

4

Carbamazepine

Facial dysmorphism

Neural tube defects

Phalynx/ fingernail hypoplasia

5

Diethylstilbestrol (DES)

vaginal clear cell carcinoma


6

Folate antagonists

Neural tube defects

7

Isotretinoin

Multiple severe birth defects

8

Lithium

ebstein anomaly (atrialized right ventricle)

9

Aethimazole

Aplasia cutis congenita

10

Phenytoin

Fetal hydantoin syndrome (cleft palate, cardiac defects, phalynx/ fingernail hypoplasia)

11

Tetracyclines

Discolored teeth

12

Thalidomide

Limb defects

13

Valproate

neural tube defects

14

Warfarin

Bone deformities

Fetal hemorrhage

Abortion

Ophthalmologic abnormalites

15

Alcohol

intellectual disability (FAS)

16

Cocaine

Placental abruption and abnormal fetal growth

17

Smoking

Low birth weight, preterm labor, placental abruptions

18

Iodine (lack or excess)

Cretinism

19

Maternal diabetes

caudal regression syndrome (anal atresia and sirenomelia)

Congeital heart defects

Neural tube defects

20

Vit A (excess)

extremely high risk for spontaneous abortions and birth defects (cleft palate, cardiac)

21

X- rays

microcephaly

intellectual disability

22

What is the mechanism of FAS?

failure of cell migration

23

2 findings in the most severe cases of FAS?

Heart Lung Fistulas

Holoprosencephaly

Decks in Step 1 Review Class (62):