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Flashcards in Micro 3 High Yield Deck (79):
1

Which parasite causes:

biliary tract disease, cholangiocarcinoma

Clonorchis sinensis

2

Which parasite causes:

Brain cysts and seizures

Taenia solium

3

Which parasite causes:

hematuria, SCC of the bladder

Schistosoma haematombium

4

Which parasite causes:

Liver (hydatid) cysts

Echinococcus granulosus

5

Which parasite causes:

Microcytic anemia

Ancylostoma, necator

6

Which parasite causes:

Periorbital edema and myalgias

Trichinella spiralis

7

Which parasite causes:

Perianal prurtitis

Enterobius

8

Which parasite causes:

Portal hypertension

Schistosoma mansoni, Shistosoma japonicum

9

Which parasite causes:

Vitamin B12 deficeincy

Diphyllobothrium latum

10

How is schistosoma contracted?

skin penetratoin

11

Which viral vaccines are live attenuated? (8)

Smallpox
Yellowfever
Rotavirus
VZV
Sabin polio virus
MMR
Influenza (intranasal)

12

What viral vaccines are killed? (4)

Rabies
Influenza (injected)
Salk polio
HAV vaccine

13

What viral vaccines are subunit vaccines? (2)

HBV
HPV

14

Which DNA virus has a ssDNA?

Parvoviridae (B19 virus)

15

Which RNA virus has a dsRNA genome?

Reoviridae

16

What are the (+)ssRNA viruses? (8)

Retrovirus
Togavirus
Flavivirus
Coronavirus
Hipevirus
Calicivirus
Picornavirus

17

Which DNA virus DOES NOT replicate in the nucleus?

Poxvirus

18

Which RNA viruses DO NOT replicate in the cytoplams?

Influenza virus
retrovirus

19

What are the NAKED DNA viruses?

PAPP

Papillomavirus, Adenovirus, Parvovirus, Polyomacirus

20

What are the NAKED RNA viruses?

CPR Hep

Calcicivirus
Picornavirus
Reovirus
Hepevirus

21

Which DNA viruses have circular genomes?

Papilloma, polyoma, hepadna (hep B)

22

Are herpesviruses naked or enveloped?

Enveloped

23

Virus that causes keratoconjunctivitis?

HSV-1

24

Which virus has owel eye inclusions?

CMV

25

Which viruses show multinucleated giant cells on Tzank smear?

HSV-1
HSV-2
VZV

26

Which virus is heterophile (+)?

EBV

27

What type of virus is HBV?

Hepadnavirus

28

"aplastic crisis in sickle cell disease, 'slapped cheeks' rash in children"

Parvovirus B19

29

What are the two polyomaviruses?

JC virus--> PML

BK virus--> targets kidney (posttransplant)

30

"flesh- colored papule with central umbilication"

Mollusicumm contagiosum (poxvirus)

31

Most common viral cause of temporal lobe encephalitis?

HSV-1

32

What are 2 complications of VZV?

Shingles
Post-herpatic neuralgia

33

What types of cells does EBV infect?

B cells (CD19+)

34

What are the atypical lymphyctes seen in EBV?

Reactive cytotoxic T cells

35

What is the monospot test?

Heterophile antibodies deteted by aggultination of sheep or horse RBCs

36

"High fever for several days that can cause seizures, followed by a diffuse macular rash"

HHV-6/ HHV-7 (Roseola)

37

Which RNA viruses are segmented?

Reoviris
Orthomyxovirus
Arenavirus
Bunyavirus

38

What is the capsid symmetry of (+)ssRNA viruses?

Icosahedral

39

Which hepatitis virus is a picornavirus?

HepA

40

Which hepatitis virus is a hepevirus?

HEV

41

Which virus is a calcivirus?

Norovirus

42

Name the 5 picornaviruses?

PERCH

Poliovirus
Echovirus
Rhinovirus
Coxsackievirus
HAV

43

Which hepatitis virus is a flavivirus?

HCV

44

Family of rubella?

Togavirus

45

Which viruses have 2 copes of the genome?

retroviruses

46

What type of virus is hantavirus?

Bunyavirus

47

What type of virus are ebola/ marburg viruses?

Filoviruses

48

How are picornaviruses contracted?

Fecal- oral

49

Which picornavirus is acid labile?

Rhinovirus (destroyed by stomach acid)

50

What are the symptoms of yellow fever virus?

High fever, black vomitus, and jaundice

51

How does rotavirus cause disease?

billod destruction with atrophy leads to decreased absorption of Na and loss of K

52

What particle promotes influenza virus entry to cells?

Hemagglutinin

53

What particle allows for influenza progeny release?

Neuraminidase

54

What causes genetic shift?

reassortment

55

What causes genetic drift?

minor mutations

56

Where does rubella rash start?

Forehead

57

What do paramyxoviruses have that causes respiratory epithelial cells to fuse and form mltinucleated cells?

F (fusion) protein

58

What are 2 symptoms of severe croup?

1- Pulsus paradoxus
2- upper airway obstruction

59

Where does measles virus begin?

Behind the ears?

60

What are 3 possible complications of Measles?

1- SSPE (subacute sclerosing panencephalitis)

2- Encephalitis

3- Giant cell penumonia

61

What vitamin can reduce measles mortality in malnourished or vitamin deficient patients?

Vit A

62

What are the 3 common symptoms of mumps?

1- Parotid
2- Orchitis
3- Aseptic meningitis

63

Bullet shaped virus associated with Negri bodies found in purkinje cells of cerebellum and hippocampus?

Rabies

64

Which heoatitis viruses have an increased risk of HCC?

HBV, HCV, HDV

65

Which is more likely to become chronic...HBV or HCV?

HCV

66

What antibody indicates immunity to HBV?

Anti-HBs

67

What might be the sole positive marker of infection during the window period of HBV?

Anti- HBc (IgM)

68

What HBV associated particle indicates high transmissiblity and active viral replication?

HBeAg

69

What HBV associated particle indicates low transmissibility?

Anti- HBe

70

What does HIV env encode?

gp120--> attachment to host CD4+ T cells

gp41--> fusion and entry

71

What does HIV gag encode for?

capsid protein

72

What does HIV pol endode for?

reverse transcriptase, aspartate prootease, and integrase

73

Coreceptor for HIV early and late?

Early- CCR5

Late- CXCR4

74

How is HIV diagnosed?

1- ELISA

then

2- Weternblot

75

AIDS defining illnesses at what CD4 count?

76

Immunocompromised with AIDS at what CD4 count?

77

What are the AIDS diseases seen at CD4

Candida albicans (oral thrush)

EBV (oral hairy leukoplaki)

Bartonella henselae

HHV-8

Cryptosporidium (chronic watery diarrhea)

HPV (SCC of anus or cervix)

78

What are the AIDS diseases seen at CD4

Toxoplasma gondii (brain abscess)

HIV dementia

JC virus (PML)

Pneumocystis jirovecii ("ground glass opacities")

79

What are the AIDS diseases seen at CD4

Aspergillus fumigatus (hemopytsis, pleurtic pain)

Cryptococcus (meningitis)

Candida albicans (esophagitis)

CMV (retinitis, esophagitis, colitis, pneumonitis)

Histoplasma capsulatum

Mycobacterium avium- intracellulare

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