Flashcards in 5/28/13 b Deck (20):
What is the function of dystrophin, the defective protein in Duchenne muscluar dystrophy?
stabilize the plasma membrane of the myocyte
Proximal muscle weakness, malaise, muscle pain, fever, irritability, and violaceous rash rash on the upper eyelids in a child?
Proximal muscle weakness preceded by a prodrome of malaise, muscle pain, fever, and irritability in a child w/o the rash.
What disease is characterized by the onset of exercise intolerance in adolescence or early adulthood w/ fatigue, muscle cramps, myalgia, myoglobinuria, muscle swelling, and fixed weakness?
McArdle's disease (glycogen storage disease type V)
What is the enzyme deficiency in McArdle's disease?
What disease is characterized by weakness/degeneration of certain muscles, joint contractures, and cardiomyopathy?
Emery-Dreyfuss muscular dystrophy
What is the best initial test for Dx of Guillain-Barre syndrome?
What tests should be used to confirm the Dx of Guillain-Barre syndrome?
electrophysiologic studies (electromyography, nerve conduction studies)
What psychiatric disorder is characterized by a pervasive pattern of disregard for the rights of others along with: failure to conform to social norms and laws, deceitfullness, irritability and aggressiveness, disregard for the safety of others, irresponsibility, and/or a lack of remorse after mistreating others?
Antisocial personality disorder
What disorder is antisocial personality disorder (necessarily) preceded by before the age of 18?
Do erythema nodosum, hilar adenopathy, and arthritis confer a good or bad prognosis upon sarcoidosis?
Do lung consolidation, black race, and extrapulmonary sarcoidosis (e.g. heart block) confer a good or bad prognosis upon sarcoidosis?
What would cause a pt w/ an acute MI to have a murmur of mitral regurgitation?
papillary muscle dysfunction
How is Technetium-99m scintigraphy useful in the management of MI?
for Dx when cardiac enzymes can't be measured (e.g. when pt presents days later or if intraoperative MI)
Carcinomas of what 3 organs comprise most bone metastases?
breast, prostate, and lungs
What is given to pts in labor before administering an epidural in order to prevent aspiration pneumonitis?
What is the first step in mgmt of a pt in whom gonorrhea infection has been established, but there is a history of adverse reaction to penicillin?
perform penicillin skin test
If the penicillin allergy skin test is positive, what may be used to treat gonorrhea if the infection is minor?
macrolides (azithromycin or clarithromycin)
How often should pts at hi ris for colon cancer receive a colonoscopy?
every 5 years