5/29/13 Flashcards Preview

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Flashcards in 5/29/13 Deck (20):
1

If a breast lesion in an older patient is suspicious on mammogram, and FNA is negative, what is the next step?

get tissue! (Core biopsy or lumpectomy) FNA is not definitive unless (+)!

2

_______ is a paraneoplastic (or primary) process usu. assoc. w/ bronchogenic carcinoma. It is characterized by bone pain, clubbing, synovial effusions, and periostosis of the tubular bones.

Hypertrophic pulmonary osteoarthropathy (HPOA)

3

What is the best initial test to investigate for a primary lung lesion, e.g. in HPOA?

CXR

4

The PTT time reflects the activity or nearly all clotting factors except ___ and XII.

VII

5

Which coagulation study is used to measure the effectiveness of heparin?

PTT

6

Which coagulation study is used to measure the activity of warfarin?

PT/INR

7

Which coagulation study, PT or PTT, does NOT take factor VII into account?

aPTT

8

When is angina stable?

when it is only induced by activity

9

Eosinophilic inclusions in the substantia nigra are seen in what disease?

Lewy body dementia

10

How is Lewy body dementia clinically different from Parkinson's with dementia?

onset of dementia is concurrent w/ motor Sx (not a year later)

11

What is the tx for anorexia nervosa (in a stable pt)?

behaviorally-based psychotherapy (e.g. CBT)

12

Baby w/ chronic constipation and distended abdomen. Rectal exam results in explosive espulsion of hard stool and flatus and relieves the abd distention. Dx?

Hirschsprung's disease

13

What is the best initial test for Hirschsprung's disease?

anorectal manometry

14

What is the connfirmatory test for Hirschsprung's disease?

full-thickness biopsy of rectal mucosa

15

What will happen to tactile fremitus in lung parenchymal consolidation?

increase

16

What will happen to tactile fremitus in leural effusion?

decrease

17

What is the normal fraction of inspired oxygen (FiO2)?

21%

18

So what is the normal PaO2/FiO2 (approx.)?

500

19

What is the mechanism of decreased pigmentation in oculocutaneous albinism?

defective production of melanin form Tyr

20

What is the mechanism of depigmentation in vitiligo?

autoimmune destruction of melanocytes