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Flashcards in More Liver and Gastro Deck (25):
1

What are the results of iron studies in pts w/ hemochromatosis: Fe, ferritin, TIBC?

Fe up
ferritin up
TIBC down

2

How do you treat hemochromatosis pts who overabsorb iron?

phlebotomy

3

How do you treat pts w/ hemochromatosis who have been over-transfused?

deferoxamine

4

Cirrhosis + choreiform movement + psyhcosis

Wilson disease

5

What is the tx for Wilson's disease?

penicillamine

6

What are the 3 tx options for chronic HBV?

interferon OR lamivudine OR adefovir

7

What is the tx of chronic HCV?

interferon + ribavirin

8

What is the first test to used to confirm suspected Wilson's disease?

serum ceruloplasmin

9

What other common complication of longstanding diabetes has a similar pathophysiology to diabetic gastroparesis?

peripheral neuropathy

10

What is the primary stimulant of gastrin release?

distention

11

What 2 drugs are used for the Tx of diabetic gastroparesis?

Erythromycin and Metoclopramide

12

What class of Abx does erythromycin belong to?

macrolides

13

What ECG abnormality can macrolides cause?

Prolonged QT interval

14

Metoclopramide is both a prokinetic and a(n) _______.

anti-emetic

15

What 2 things cause dizziness, sweating in dumping syndrome?

hypoglycemia and intravascular volume depletion

16

Whish type of IBD is ANCA+?

UC

17

Which type of IBD is ASCA+?

Crohns

18

Name 3 adverse effects of sulfasalazine (for the 10-30% of the population w/ sulfa sensitivity).

rash, hemolysis, and renal problems

19

What specific renal problem does sulfasalazine cause?

Allergic Interstitial Nephritis

20

What steroid is used for acute exacerbations of IBD?

Budesonide

21

Why is budesonide the steroid of choice for IBD exacerbations?

highly susceptible to first-pass effect --> no systemic efftects!

22

The first line drugs for chronic IBD are all derivatives of what?

mesalamine

23

The 3 main mesalamine-based drugs for IBD all have what 3 letters in their names?

ASA - Pentasa (or 5-ASA), AsaCol, and Rowasa

24

What 2 other immunomodulant drugs (not mesalamine) are used chronically for IBD?

6-MP, azothioprine

25

What Abx are used to prevent perirectal/perianal disease in Crohns?

Vanco, metro