Flashcards in 5/28/13 Deck (18)
Name 2 cholinesterase inhibitors, aside from donepezil, that are used to tx Alzheimer's.
Rivastigmine and Galantamine
(Don quijote, the Gallant knight, jumped the River, only to find that his princess had Alzheimer's.)
What sort of an arrhythmia could convert to SVT or VT if treated w/ anti-arrhythic Ca++ channel blockers, β-blockers, or digoxin?
Wolff-Parkinson-White Pre-excitation syndrome
Which are the 2 main anti-arrhythmic Ca++ channel blockers?
verapimil and diltiazem
What is the mechanism by which CA++-channel blockers, β-brockers, and digoxin may instigate an arrhythmia in WPW syndrome?
slowed conduction through AV node increases conduction through accessory bundle of Kent
What are the first 3 steps in neonatal rescuscitation in the delivery room?
place under radiant warmer, dry, and stimulate
In most cases just after birth, when a depressed neonate is not resuscitated by radiant warmer, drying, and stimulation, wehat is the best next step?
positive pressure ventilation w/ bag mask
Just after delivery, the neonate is depressed and there was meconium-stained amniotic fluid. What is the first step?
intubation and tracheal suction
Why should intubation and suctioning begin before drying the depressed neonate w/ meconium stained amniotic fluid?
prevent meconium aspiration on first cry
_______ presents in childhood w/ fatigue, muscle cramps, exersize intolerance, exertional rhabdomyolysis, and hemolysis.
_______ presents w/ some degree of pallor, jaundice, and splenomegaly. Increased reticulocytes, mild microcytosis, and polychromatophilia are characteristic.
Pyruvate kinase deficiency
WHat is the mechanism by which G6PD levels can be falsely normal after an episode of hemolysis in a G6PD deficient pt?
the most deficient cells are lysed
Name some drugs that cause drug-induced hemolytic anemia?
Penicillins, allopurinol, phenytoin, rifampin
What is usually used to prophylax close contacts of pts w/ gonococcal meningitis?
What is used in HIV pts who have had cryptococcus for prophylaxis against future infection?
Why would a pt w/ cirrhosis have a lo Ca++ level? Why doesn't it matter?
total calcium = free ionized Ca + Ca-albumin; only free Ca is physiologically relevant
WHich is worse, alpha-thalassemia minor or beta-thalassemia major?
What treatment is usu. required for beta thalassemia major (not trait)?
lifelong transfusions and iron chelation