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Flashcards in UWorld 1 Deck (25):
1

What would you suspect as a cause of macrocytic anemia in a pt w/ vitiligo or Hashimoto's thyroiditis?

pernicious anemia

2

_______ is defined as the presence of Sx of schizophrenia along with mood Sx (major depression, bipolar disorder, or a mixed episode).

Schizoaffective disorder

3

_______ should be suspected in pts w/ blunt thoracic trauma who remain tachypneic and hypotensive despite aggressive fluid resuscitation. Classic X-ray findings reveal multiple rib fractures overlying a lung contusion.

Flail chest

4

What cranial injury causes a biconvex hematoma on CT?

epidural hematoma

5

What cranial injury appears as a uniconvex (semilenticular) hematoma on CT?

subdural hematoma

6

What are the most common sites of hypertensive intracerebral hemorrhage?

putamen and thalamus

7

What is the first-line drug for seizures in the emergency setting (e.g. status epilepticus)?

benzos (lorazepam)

8

What is the 2nd line Tx for seizures in the emergency setting?

phenytoin

9

What is the most common primary bone tumor affecting children and young adults?

osteosarcoma

10

What is the typical PE finding in osteosarcoma?

tender soft-tissue mass

11

What are the classic x-ray findings of osteosarcoma?

ssunburst pattern and Codman's triangle (periosteal elevation)

12

What is the typical x-ray finding in Ewing's sarcoma?

onion-skin periosteal rxn

13

Where does osteosarcoma usu occur generally? What specific 3 sites are seen most often?

metaphysis of long bones; distal femur, proximal tibia, proximal humerus

14

What will happen to methylmalonic acid levels in B12 def?

build up

15

What will happen to methylmalonic acid levels in B6 def?

no change

16

What substance will accumulate in the blood in both B6 and B12 def?

homocysteine

17

_______ classically presents as a brawny, edematous, erythematous, cutaneous plaque w/ a "peau d'orange" appearance overlying a breast mass.

Inflammatory breast carcinoma

18

What is the most vcommon cause of hypercalcemia in ambulatory pts?

primary hyperparathyroidism

19

What is the most common cause of primary hyperparathyroidism?

parathyroid adenoma

20

Indomethacin and hydrochlorothiazide are used in the Tx of what kind of diabetes insipidus?

nephrogenic

21

A holosystolic murmur at the lower sternum that increases w/ inspiration is most likely _______.

tricuspid regurgitation

22

What antibiotic should be used as empiric tx for endocarditis in an IV drug abuser?

vancomycin

23

What is the most common cause of hypercalcemia in hospitalized pts?

malignancy, of course

24

How does sarcoidosis cause increased serum calcium levels?

increased conversion of 25-OH vit D to 1,25-OH vit D in granulation tissue

25

For a pt w/ 0-1 risk factors for coronary artery disease, what is the LDL cutoff for starting medication?

190 mg/dL