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Flashcards in HY Pharm 4 Deck (25)
1

The most common neurologic abnormality in chronic alcoholics

*Peripheral neuropathy (also HTN, anemia, and MI)

2

Drugs of choice for generalized tonic-clonic and partial seizures

*Valproic acid, Phenytoin and Carbamazepine

3

Drugs of choice for absence seizures

*Ethosuximide and valproic acid

4

Drug of choice for myoclonic seizures

*Valproic acid

5

Anti-seizure drugs used also for pain of neuropathic orgin

*Gabapentin

6

SE of phenytoin

Diplopia, ataxia, nystagmus, gingival hyperplasia (DANG)

7

DOC for malignant hyperthermia that may be caused by use of halogenated anesthetics

*Dantrolene

8

Benzodiazepine receptor antagonist, it accelerates recovery from benzodiazepine overdose

*Flumazenil

9

Opioid associated with awareness during surgery and post-operative recall, but still used for high-risk cardiovascular surgeries

*Fentanyl

10

DOC for malignant hyperthermia by acting on the sacroplasmic reticulum of skeletal muscle

*Dantrolene

11

Causes of drug induced Parkinsonism

Antipsychotics
Reserpine at high doses
MPTP (by-product of illicit meperidine analog)

irreversible

12

Side effects occuring in antipsychotics that block dopamine

*EPS, hyperprolactinemia, amennorrhea, galactorrhea, neuroleptic malignant syndrome

13

Atypical antipsychotic causing high prolactin levels

*Risperidone

14

Drug used in neuroleptic malignant syndrome

*Dantrolene

15

Antipsychotics having the strongest autonomic effects

*Chlorpromazine or Thioridazine

16

Agent with greater affinity to 5HT2A receptor; reserved for refractory schizophrenia, and can cause weight gain and agranulocytosis

*Clozapine (H1 blocker)

17

Anti-psychotics shown not to cause tardive dyskinesia

*Clozapine and quetiapine

18

Major route of elimination for Lithium

*Kidneys

19

DOC for bipolar affective disorder

*Lithium

20

SE of lithium

*Tremor/excitation, ataxia, aphasia, HYPOTHYROIDISM, and reversible diabetes insipidus

21

HIV antiviral class known to have severe drug interactions by causing inhibition of metabolism

*Protease inhibitors

22

DOC for N. gonorrhea

*Ceftriaxone

23

DOC for herpes and its MOA

*Acyclovir; activates thymidine kinase

24

Anti-microbials that cause hemolysis in G6PD-deficient patients

*Sulfonamides

25

SE of Protease inhibitors

Lipodystrophy, kidneys stones, inhibits P450 (don't use rifampin)